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http://dx.doi.org/10.1089/jpm.2025.0056 | DOI Listing |
Front Neurol
February 2025
Department of Child and Adolescent Health, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Objective: To examine the association of ADHD and LD with visual impairment, uncorrected refractive error, and refractive error (myopia, hyperopia, and astigmatism) among US children and adolescents.
Method: A population-based cross-sectional study included 3,385 participants aged 12-15 years from the large, representative sample of US NHANES. The diagnoses of ADHD and LD in children and adolescents, as reported by parents or adolescents themselves, were analyzed.
Front Bioinform
February 2025
School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Machine learning and genomic medicine are the mainstays of research in delivering personalized healthcare services for disease diagnosis, risk stratification, tailored treatment, and prediction of adverse effects. However, potential prediction errors in healthcare services can have life-threatening impact, raising reasonable skepticism about whether these applications have practical benefit in clinical settings. Conformal prediction offers a versatile framework for addressing these concerns by quantifying the uncertainty of predictive models.
View Article and Find Full Text PDFHeliyon
February 2025
Department of Mathematıcs, Firat University, 23119 Elazig, Turkiye.
The equations describe the behavior of steady state flow in porous medium generally results in elliptic partial differential equations with coefficient represents the permeability of the medium. This article presents the extension of mortar mixed method for second order nonlinear elliptic equations that describes flow in porous media. The domain is decomposed into non-overlapping regions with each partitioned independently.
View Article and Find Full Text PDFJ Sci Comput
March 2025
MOX, Dipartimento di Matematica, Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milan, Italy.
The computational effort entailed in the discretization of fluid-poromechanics systems is typically highly demanding. This is particularly true for models of multiphysics flows in the brain, due to the geometrical complexity of the cerebral anatomy-requiring a very fine computational mesh for finite element discretization-and to the high number of variables involved. Indeed, this kind of problems can be modeled by a coupled system encompassing the Stokes equations for the cerebrospinal fluid in the brain ventricles and Multiple-network Poro-Elasticity (MPE) equations describing the brain tissue, the interstitial fluid, and the blood vascular networks at different space scales.
View Article and Find Full Text PDFJ Biomol Struct Dyn
March 2025
Biomedical Instrumentation Unit, CSIR-Central Scientific Instruments Organisation (CSIR-CSIO), Chandigarh, India.
Jaundice is a well-studied condition in many countries. It affects 70% of newborns and is a significant contributor to both illness and death. Although benign, it can cause persistent hearing impairment, athetosis, and intellectual disabilities.
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