Objective: Lumbar disc herniation is a syndrome triggered by degenerative changes in the intervertebral disc. Based on the technique of ALIF, combining the concept of Anterior Cervical Discectomy and Fusion (ACDF), we summarized Anterior Lumbar Discectomy Fusion (ALDF) in our previous clinical experience. This study is to explore the clinical efficacy and safety of this method for treating lumbar disc herniation.
Method: We retrospectively analyzed the medical records of 44 patients with L5/S1 lumbar disc herniation treated in the Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, from December 2020 to April 2023. The Japan orthopaedic association (JOA) scoring system, Oswestry disability index (ODI), and Numerical rating scale (NRS, to evaluate pain) were used to assess patients' clinical symptoms before and after surgery. Radiographic examinations, including X-ray, CT, and MRI, were performed to record preoperative and postoperative imaging indicators, such as surgical segment, intervertebral disc height, and dural sac cross-sectional area. Postoperative follow-up records noted the time of bony fusion and postoperative complications.
Results: All 44 patients successfully completed the ALDF operation. No vascular, ureteral, or abdominal organ damage occurred during the operation. All patients' symptoms were alleviated. Postoperative CT scans revealed a significant improvement in intervertebral disc height (7.32 ± 2.07 mm vs. 12.15 ± 1.79 mm, p < 0.05). Postoperative MRI scans showed a significant increase in the cross-sectional area of the dural sac (0.95 ± 0.33cm vs. 1.30 ± 0.37cm, p < 0.05). X-ray re-examination 6 months after surgery showed bony fusion in all operated segments. 12 months postoperatively, the average JOA was 25.57 ± 2.29, ODI was 4.45 ± 3.43%, and NRS was 1.43 ± 1.13, all significantly improved compared to preoperative levels, p < 0.05. There were no complications such as implant failure, cage subsidence, or wound infection.
Conclusion: ALDF provides an effective treatment strategy for patients with lumbar disc herniation. This procedure allows direct removal of protruding discs and calcified posterior longitudinal ligaments under the microscope, achieving the goal of direct decompression of the surgical segment. At the same time, it can reduce the damage to posterior muscles and skeletal structures caused by surgery. Comprehensive preoperative assessment and meticulous microscopic operation can help avoid complications such as nerve and vascular injuries.
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http://dx.doi.org/10.1186/s12891-025-08390-9 | DOI Listing |
Foraminal and extraforaminal lumbar disc herniations are common sources of pain and disability. Classic surgical treatments, such as open approach through Witsel technique, often involve resection of the superior articular process to decompress the foraminal space. Unilateral biportal endoscopy (UBE) has emerged as a minimally invasive alternative, providing enhanced visualization and precision while minimizing soft tissue damage.
View Article and Find Full Text PDFBMC Musculoskelet Disord
March 2025
Department of Radiology, Zigong Fourth People's Hospital, Zigong, 643000, Sichuan Province, China.
Background: Low back pain(LBP) is very common among the population, and intervertebral disc(IVD) degeneration is considered to be the most common cause of LBP, but the pathophysiological process between IVD degeneration and LBP is not very clear. We conducted this study to clarify the interplay between quantitative magnetic resonance imaging (MRI) parameters, including q-Dixon and T2 mapping, and clinical symptomatology in patients with LBP.
Methods: All LBP patients underwent lumbar spine MRI, encompassing q-Dixon and T2 mapping.
Int J Spine Surg
March 2025
Atrium Health, Spine Center of Excellence, Charlotte, NC, USA
Int J Spine Surg
March 2025
Department of Neurosurgery, Hospital Lusíadas Porto, Porto, Portugal.
The evolution of spinal arthroplasty, a significant journey that began in the 1960s and 1970s, has seen remarkable progress. Initially designed to preserve motion at spinal segments and avoid complications associated with fusion surgeries, early designs faced setbacks due to rudimentary concepts and limited materials. However, the 1980s marked a turning point with the development of modern total disc replacement concepts, utilizing advanced materials such as titanium and polyethylene to improve implant longevity and integration.
View Article and Find Full Text PDFSpine (Phila Pa 1976)
March 2025
Chicago Anesthesia Pain Specialists, Chicago, IL, USA.
Study Design: An exploratory analysis of a randomized, double-blind, sham-controlled, phase 3 study.
Objective: To evaluate the impact of SI-6603 (condoliase) on health-related quality of life (HRQoL)-related outcomes in patients with lumbar disc herniation (LDH)-associated radicular leg pain from the Discovery 6603 study (NCT03607838).
Summary Of Background Data: Condoliase is a novel chemonucleolytic agent that selectively degrades chondroitin sulfate in the nucleus pulposus.
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