AI Article Synopsis

  • Forty-five patients underwent intrauterine insemination between October 1981 and August 1983 due to various fertility issues, including poor semen quality and cervical mucus problems.
  • A total of 374 inseminations were conducted over 163 cycles, resulting in eight pregnancies, which equates to a pregnancy rate of 17.4%.
  • The data suggested a possible cause-and-effect relationship since five pregnancies occurred after the first insemination cycle, indicating that further trials of this method in selected patients could be beneficial.

Article Abstract

Forty-five patients initiated intrauterine insemination between October 1981 and August 1983. Indications for insemination included poor semen (count less than 20 X 10(6)/ml and/or motility less than 40%), poor cervical mucus, presence of sperm antibodies, unexplained poor postcoital tests, or various combinations of the above. During this time period, 374 inseminations were performed in 163 cycles and resulted in eight pregnancies in the 45 patients receiving artificial insemination by homologous donor, for an overall pregnancy rate of 17.4%. The fact that five of the pregnancies occurred in the first insemination cycle and two in the second cycle was felt to indicate a cause-and-effect relationship. A trial of intrauterine insemination in selected patients would appear to be warranted.

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http://dx.doi.org/10.1016/s0015-0282(16)48558-4DOI Listing

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