A novel supramolecular metallogel, termed Hg-SA, was synthesized using succinic acid (SA) as a low molecular weight gelator in a DMF solvent under standard conditions. The mechanical properties of the Hg-SA metallogel were evaluated through rheological tests, specifically focusing on the angular frequency and strain sweep measurements. Field emission scanning electron microscopy (FESEM) results revealed the rod-like network structure of Hg-SA, while energy dispersive X-ray (EDX) elemental mapping confirmed its composition. Fourier transform infrared (FT-IR) spectroscopy provided insights into the formation mechanism of the synthesized Hg-SA metallogel. The antimicrobial activity of the metallogel was tested against Gram-positive bacteria and as well as Gram-negative bacteria and , revealing its significant antibacterial potency. Thus, this study highlights the antimicrobial effects of Hg(ii)-based succinic acid-mediated metallogels against Gram-positive and Gram-negative bacteria.
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http://dx.doi.org/10.1039/d4ra08575b | DOI Listing |
Acta Crystallogr E Crystallogr Commun
March 2025
A new cobalt complex, bis-[tris-(amino-thio-urea)cobalt(III)] bis-[2-(carb-oxy-methyl)-2-hy-droxy-butane-dioato]cobalt(II) tetra-nitrate tetra-hydrate, [Co(CHNS)][Co(CHO)](NO)·2HO, designated as [Co(tsc)][Co(cit)](NO)·4HO, was synthesized. Two crystallographically independent cobalt centers are present. In the first, the central metal atom is chelated by three thio-semicarbazide ligands in a bidentate fashion whereas the second, positioned on a crystallographic inversion center, is hexa-coordinated by two citrate anions in a distorted octa-hedral geometry.
View Article and Find Full Text PDFAnal Methods
March 2025
Gansu Key Laboratory of Efficient Utilization of Oil and Gas Resources, Gansu Key Laboratory of Protection and Utilization for Biological Resources and Ecological Restoration, College of Petroleum and Chemical Engineering, Longdong University, Qingyang 745000, P. R. China.
In this study, a novel linear supramolecular polypseudorotaxane was synthesized using a pillar[5]arene derivative (CP5) as the host and bis-bromohexyl pillar[5]arene (DP5) as the guest, facilitated by host-guest interactions. Subsequently, these components self-assembled to create an AIE-active material (CPDP-G) through C-H⋯π interactions involving the pillar[5]arene groups. Notably, the CPDP-G fluorescence material exhibits an exceptionally sensitive response to Fe, with a detection limit of 0.
View Article and Find Full Text PDFJ Am Chem Soc
March 2025
State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200241, China.
Elucidating the underlying mechanism of effective chirality and energy transfer processes observed in biological assemblies has cross-disciplinary significance, and it is of special interest in the fields of chemistry and biology due to the pivotal role of chirality in life. Challenges in the field include how to achieve real-time monitoring of the chirality and energy transfer dynamics simultaneously, as well as how to distinguish whether these processes take place in the ground or excited state. Herein, we achieve the first attempt at real-time observation of the concerted ultrafast dynamics between the Förster resonance energy transfer (FRET) and the generation of circularly polarized luminescence (CPL) in the excited state in near-infrared CPL supramolecular nanofibers (SNFs) by using femtosecond time-resolved circularly polarized luminescence (fs-TRCPL) spectroscopy.
View Article and Find Full Text PDFOf the 1.5 million emergency room visits each year in the United States due to flexor tendon injuries in the hand, over 30-40% result in peritendinous adhesions which can limit range of motion (ROM) and severely impact an individual's quality of life. Adhesions are fibrous scar-like tissues which can form between adjacent tissues in the body in response to injury, inflammation, or during normal healing following surgery.
View Article and Find Full Text PDFBiomacromolecules
March 2025
Department of Biomedical Engineering, College of Design and Engineering, National University of Singapore, 15 Kent Ridge Crescent, Singapore 119276, Singapore.
A novel blood-brain barrier (BBB)-penetrating supramolecular gene delivery system was developed utilizing a host-guest block-building strategy to systematically screen and optimize various block compositions. Linear poly(ethylene glycol) (PEG) was coupled with hydrophobic poly[(,)-β-hydroxybutyrate] (PHB) blocks of varying lengths with an adamantyl (Ad) end, giving the PEG-PHB-Ad guest polymers, which were complexed with the cationic 4-arm star-shaped β-cyclodextrin-poly(2-dimethylaminoethyl methacrylate) (βCD-pDMAEMA) host polymer, resulting in the formation of linear-star pseudoblock PEG-PHB-Ad/βCD-pDMAEMA copolymers. These amphiphilic supramolecular copolymers were thoroughly characterized and assessed for the formation of DNA micelleplex nanoparticles as a gene delivery system.
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