The thermoluminescence dosimeter (TLD) sheet is a measurement device coated with manganese-doped LiBO in sheet form. The sheet is 0.2-mm thick and flexible. Hence, it can fit and be installed on irregular surfaces. The current study aimed to evaluate the feasibility of measuring patient surface doses during radiation therapy using TLD sheets. Further, the surface doses when using a three-dimensional (3D) printed bolus were compared. First, calibration of the between TLD sheet measurements and the irradiation doses was performed. Second, dose calculations and TLD sheet measurements were compared to evaluate the error between treatment planning system (TPS) dose calculations and surface dose measurements. Finally, the TLD sheet was fitted to the head phantom to measure the surface dose at the uneven areas under two conditions (with a commercial [CM] bolus and a 3D-printed bolus). Based on the error from the dose calculation algorithm and the difference between the TLD sheet thickness and the dose grid size or evaluation structure volume, the differences between the TLD sheet measurements and the treatment plan doses were up to 68.6% for the X-ray collapsed cone convolution (CCC) method and up to 8.4% for the electron beam Monte Carlo (MC) method. Based on the results of the surface dosimetry of the head phantom, the application of surface dosimetry, particularly skin dosimetry, even on uneven body surfaces, can be feasible.
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http://dx.doi.org/10.1002/acm2.70035 | DOI Listing |
J Appl Clin Med Phys
February 2025
Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.
The thermoluminescence dosimeter (TLD) sheet is a measurement device coated with manganese-doped LiBO in sheet form. The sheet is 0.2-mm thick and flexible.
View Article and Find Full Text PDFJ Mater Chem B
September 2023
Department of Biochemical Engineering, School of Chemical Engineering and Technology and Key Laboratory of Systems Bioengineering and Frontiers Science Center for Synthetic Biology (Ministry of Education), Tianjin University, Tianjin 300350, China.
Photo-oxygenation has emerged as an effective modality for scavenging Alzheimer's amyloid-β (Aβ) plaques. However, limitations of the current photo-oxidants, such as low Aβ-targeting and single functionality, hinder the scavenging of Aβ plaques photo-oxygenation. Herein, based on an aggregation-induced emission (AIE)-active fluorogen (named TPMD), we designed AIE photo-oxidant nanoparticles (T-LD NPs) for Aβ imaging, inhibition, and disaggregation.
View Article and Find Full Text PDFLuminescence
August 2021
Department of Physics, R.T.M. Nagpur University, Nagpur, India.
In this study, thermoluminescence detectors (TLD)-600 and TLD-700 were used under different conditions to study neutron dosimetry for its application in medical dosimetry as albedo dosimeters. LiF has a high cross-section for neutrons and is more sensitive to neutrons than to gamma radiation. Conversely, TLD-700 showed a better response to gamma radiation.
View Article and Find Full Text PDFJ Appl Clin Med Phys
April 2021
Department of Radiation Physics and Technology, Southern Tohoku Proton Therapy Center, Fukushima, Japan.
Purpose: This study aimed to evaluate the dosimetric properties of a newly developed thermoluminescent sheet-type dosimeter (TLD-sheet) for clinical proton beams.
Materials And Methods: The TLD-sheet is composed mainly of manganese doped lithium triborate, with a physical size and thickness of 150 mm × 150 mm and 0.15 mm respectively.
J Cancer Res Ther
March 2019
Department of Medical Physics and Medical Engineering, Tehran University of Medical Sciences, Tehran, Iran.
Aim: By necessity of dosimeters calibration for evaluating delivered dose accuracy to organs out of the radiation field in patients undergoing gamma knife radiosurgery, we calibrated thermoluminescence dosimeters in gamma knife and Co instruments, and then, compared both results to investigate when one of these devices was out of reach, can we use one of this instruments instead of the ther.
Materials And Methods: To individual calibration by Co, thermoluminescent dosimeters (TLDs) were placed in a Perspex sheet with conditions of source-skin distance = 80 cm, field size = 10 cm × 10 cm, and dose = 100 cGy. For individual calibration by Gamma knife, TLDs placed in flat Perspex were located in a special sphere and were exposed with conditions of source to axis distance = 40 cm, field size = 18 mm, and dose = 100 cGy, and for group calibration, TLDs were divided into six groups and were exposed with doses of 0-1000 cGy in both devices.
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