Background: Severe asthma (SA) is characterised by persistent asthma symptomatology despite adherence to intensive treatment and control of asthma triggers. It is estimated that approximately 50% of individuals with SA have current employment, considerably less than rates in the general population. Poor physical and mental health status have been suggested as a potential explanation for this, but the relationship has not been investigated in depth. We investigated how bio-psycho-social and cultural factors influence work ability and employment in SA patients.

Methods: Participants were recruited from the Birmingham Regional NHS Severe Asthma Service via opportunity sampling, with the exclusion criteria being individuals who had never been employed, currently in full-time education, or non-English speakers. Subsequently, men and those with minority-ethnic backgrounds were purposefully selected to gain a balanced sample. Interviews were performed either face-to-face, online or via telephone, transcribed using software and edited manually. Data were analysed using Reflexive Thematic Analysis.

Results: The study included 12 participants (9 females and 3 males). Four major themes were constructed: impact of patients' asthma control on work, psychological burden of living with SA, costs and benefits of being in employment, and adaptations and strategies for remaining in employment.

Conclusions: Our findings highlight the potential for physical, occupational, psychological, and social support to address the diverse job-related difficulties experienced by people with SA. Additionally, national policy reforms should be considered to improve work capacity and promote employment opportunities.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11834327PMC
http://dx.doi.org/10.1186/s12890-025-03499-yDOI Listing

Publication Analysis

Top Keywords

severe asthma
12
work ability
8
asthma
6
employment
5
'stuck catch-22'
4
catch-22' qualitative
4
qualitative study
4
study perceived
4
work
4
perceived work
4

Similar Publications

Background And Aim: Children and young people (CYP) with severe, sub-optimally controlled asthma and co-existing allergic senitization to indoor aeroallergens, such as pet dander and house dust mite (HDM), would likely benefit from reduced allergen exposure. Multiple allergen remediation interventions exist and are often suggested to families in secondary care asthma clinics in the United Kingdom. Evidence suggests remediation uptake is low or partial but there is sparse evidence to explain why.

View Article and Find Full Text PDF

Rationale: Bronchoscopic lung volume reduction treatment using endobronchial valves (EBV) is an effective treatment for severe COPD patients by improving lung function and quality of life. However, little is known about its effects on systemic inflammation. Therefore, the aim of our study was to investigate whether EBV treatment impacts the inflammatory cytokine profile.

View Article and Find Full Text PDF

Natural killer cells in the lung: novel insight and future challenge in the airway diseases.

ERJ Open Res

March 2025

Respiratory Diseases Unit, Department of Medical Sciences, Surgery and Neurosciences, Siena University Hospital, Siena, Italy.

Natural killer (NK) cells are innate lymphoid cells which are present in the lung as circulating and resident cells. They are key players both in airway surveillance and in crosstalk with (COPD) pathogenesis, and they seem to contribute to the development of bronchiectasis. In asthma, NK cell dysfunction was observed mainly in severe forms, and it can lead to a biased type-2 immune response and failure in the resolution of eosinophilic inflammation that characterise both allergic and eosinophilic phenotypes.

View Article and Find Full Text PDF

Different Modalities in the Management of Post-COVID-19 Olfactory Dysfunction.

Indian J Otolaryngol Head Neck Surg

January 2025

Otorhinolaryngology Department, Faculty of Medicine, Benha University, Benha, Qalyubia Egypt.

SARS-CoV-2 infection may lead to olfactory dysfunctions affecting patients' quality of life. Despite various ongoing studies, solid evidence supporting therapies, especially for COVID-19-related olfactory dysfunction, remains scarce. To assess nasal steroid, nasal vitamin A, and intranasal theophylline as treatment options for post-COVID-19 olfactory dysfunction.

View Article and Find Full Text PDF

Corticosteroid treatment sometimes causes psychiatric side effects such as mania, depression, and psychosis. It is believed that exogenous corticosteroids lead to dysregulation of corticosteroid signaling and neurotransmitters in a dose-dependent manner. Therefore, the administration of corticosteroids is at risk of worsening bipolar disorder.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!