We evaluated antibiotic prescribing practices for neonates and infants hospitalized with infections in resource-constrained healthcare settings, where antimicrobial resistance is responsible for significant neonatal morbidity and mortality. A point prevalence survey of 667 admitted infants across 10 clinical sites in Southeast Asia revealed a total of 405 antibiotics were prescribed to 218 infants, with high use of World Health Organization-classified "Watch," "Reserve" and "Not Recommended" antibiotics.
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http://dx.doi.org/10.1097/INF.0000000000004614 | DOI Listing |
JAC Antimicrob Resist
April 2025
USAID Medicines, Technologies, and Pharmaceutical Services (MTaPS) Program, Management Sciences for Health, 4201 N. Fairfax Dr., Suite 500, Arlington, VA, USA.
Background: The Global Leaders Group on Antimicrobial Resistance (AMR) beckoned nations to share surveillance data on antimicrobial consumption (AMC) and AMR while promoting access to essential antimicrobials in countries with the highest burden of AMR.
Objectives: To analyse findings of the national-level AMC (years 2020-2022), building on our prior work (2017-2019), and to assess any emerging trends.
Methods: Data were obtained from the Tanzania Medicines and Medical Devices Authority, Tanzania Medical Stores Department, and from local manufacturers.
J Infect Chemother
February 2025
Laboratory of Clinical Pharmacoepidemiology, Kyoto Pharmaceutical University, Kyoto, Japan. Electronic address:
Integrating the automated collection of antimicrobial use metrics into national surveillance systems is vital for antimicrobial stewardship evaluation. The days of antibiotic spectrum coverage (DASC) serves as a quantitative metric for assessing de-escalation strategies. A major challenge is that DASC has not yet been integrated into the national surveillance system, partly owing to the omission of commonly used antibiotics in Japan in the initially developed antibiotic spectrum coverage (ASC) scores.
View Article and Find Full Text PDFResearch Objectives: to investigate possible links between antibiotic consumption levels, with subsequent improvement of approaches to enhance antibiotic use effectiveness and curb antibiotic resistance growth.
Inclusion Criteria: the inclusion criteria were antibacterial drugs for systemic use.
Materials And Methods: In this study, we selected 2 multidisciplinary hospitals in Almaty.
Antibiotics (Basel)
February 2025
The Eastern Mediterranean Public Health Network (EMPHNET), Dhaka 1212, Bangladesh.
To aid in the development of antimicrobial stewardship programs (ASPs), we analyzed the patterns and trends in antibiotic prescriptions for patients with severe acute respiratory infection (SARI), utilizing the WHO's AWaRe classification. We analyzed data from hospital-based influenza surveillance from January 2011 to December 2020 across nine Bangladeshi tertiary-level hospitals. Surveillance physicians collected WHO-defined SARI patient data, including demographics, clinical characteristics, and antibiotic prescriptions.
View Article and Find Full Text PDFAntibiotics (Basel)
February 2025
Laboratory of Microbiology, Charles Nicolle Hospital, Tunis 1006, Tunisia.
The exponential rise of bacterial resistance poses a threat to antibiotic efficacy, with a great impact on public health. This study aims to analyze the correlation between antibiotic consumption and the emergence of bacterial resistance. Conducted retrospectively at Charles Nicolle Hospital in Tunis, Tunisia, from 2010 to 2022, this study was based on STKMED software for antibiotic consumption data, hospital administrative records for the number of hospitalization days, and SIRSCAN software for bacteriological data.
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