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Using normative models pre-trained on cross-sectional data to evaluate intra-individual longitudinal changes in neuroimaging data.
Elife
March 2025
Department of Complex Systems, Institute of Computer Science of the Czech Academy of Sciences, Prague, Czech Republic.
Longitudinal neuroimaging studies offer valuable insight into brain development, ageing, and disease progression over time. However, prevailing analytical approaches rooted in our understanding of population variation are primarily tailored for cross-sectional studies. To fully leverage the potential of longitudinal neuroimaging, we need methodologies that account for the complex interplay between population variation and individual dynamics.
View Article and Find Full Text PDFAssociations of Device-Measured Physical Activity and Sedentary Time With Neural Responses to Visual Food Cues in Adults: A Functional Magnetic Resonance Imaging Study.
Hum Brain Mapp
March 2025
National Centre for Sport and Exercise Medicine, School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.
Self-reported physical activity is associated with lower brain food cue responsiveness in reward-related regions, but relationships utilizing objective physical activity measurement tools have not been explored. This cross-sectional study examined whether device-measured moderate-to-vigorous intensity physical activity and sedentary time are related to neural responses to visual food cues using functional magnetic resonance imaging. Fifty-one healthy adults (30 men, 21 women; mean ± SD: age 26 ± 6 years; body mass index 24.
View Article and Find Full Text PDFApplication of Near-Infrared Spectroscopy in Early Detection of Antidepressant Treatment Efficacy in Major Depressive Disorder: A Longitudinal Study.
Actas Esp Psiquiatr
March 2025
Severe Female Ward, Wenzhou Seventh People's Hospital, 325000 Wenzhou, Zhejiang, China.
Background: Major depressive disorder (MDD) is a prevalent and debilitating mental health condition, necessitating early detection and effective treatment strategies. Near-infrared spectroscopy (NIRS) is a promising neuroimaging technique for monitoring cerebral hemodynamics and may serve as an objective biomarker for MDD diagnosis and treatment efficacy. This study aimed to investigate the utility of NIRS in the early detection and longitudinal monitoring of antidepressant treatment efficacy in MDD patients.
View Article and Find Full Text PDFSex differences in electrical activity of the brain during sleep: a systematic review of electroencephalographic findings across the human lifespan.
Biomed Eng Online
March 2025
KITE Toronto Rehabilitation Institute, University Health Network, 550 University Avenue 11th Floor, Rm 11-183, Toronto, ON, M5G 2A2, Canada.
Background: With the explosion of techniques for recording electrical brain activity, our recognition of neurodiversity has expanded significantly. Yet, uncertainty exists regarding sex differences in electrical activity during sleep and whether these differences, if any, are associated with social parameters. We synthesised existing evidence applying the PROGRESS-Plus framework, which captures social parameters that may influence brain activity and function.
View Article and Find Full Text PDFAlteration of cortical structure and functional connectivity in childhood trauma.
Neuroscience
March 2025
The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou 510370, China; Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China. Electronic address:
Childhood trauma acts as an independent risk factor for mental disorders. This study utilized multi-modal MRI techniques to integrate cortical structural measurements and functional connectivity (FC) to identify neurobiological markers of trauma. This study recruited 215 participants, divided into a trauma group (n = 57) and a well-matched non-trauma group (n = 158) based on the childhood trauma questionnaire.
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