With the rapid advancement of modern communication technologies, safeguarding information against forgery and unauthorized access has become increasingly critical, driving interest in advanced optical encryption systems. These systems excel in parallel image data processing, enabling swift detection and verification of sensitive information. However, traditional light-based encoding methods are constrained by their limited dependence on static parameters such as light wavelength and intensity and lack dynamic, reversible adaptability. To overcome these limitations, we propose an optical cryptography system that utilizes the tunable color and polarization selectivity of in situ polymerized, multicolor patterned chiral liquid crystals. This system capitalizes on the multifunctional optical properties of chiral liquid crystals, including thermally induced phase transitions that allow reversible and repeatable tuning, rendering encoded information unidentifiable until specific conditions are met. Furthermore, the system incorporates advanced disguising mechanisms through color separation, revealing accurate information only under predefined conditions. Key to its enhanced functionality is the integration of circular polarization selectivity, enabling electrically switchable polarization separation. This feature facilitates the display of distinct information under right- or left-handed circularly polarized light. By exploiting the dynamic optical properties of chiral liquid crystals, our system offers a multilevel encryption platform that significantly enhances data security. This versatile approach surpasses the limitations of conventional methods, providing a robust solution for secure data encoding and anticounterfeiting applications.
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http://dx.doi.org/10.1021/acsami.4c21290 | DOI Listing |
Chem Sci
March 2025
Ōmura Satoshi Memorial Institute, Graduate School of Infection Control Sciences, Kitasato University 5-9-1 Shirokane, Minato-ku Tokyo 108-8641 Japan
Macrocyclic peptides, including depsipeptides, are an emerging new modality in drug discovery research. Tetraselide, an antifungal cyclic peptide isolated from a marine-derived filamentous fungus, possesses a unique amphiphilic structural feature consisting of five consecutive β-hydroxy-amino acid residues and fatty acid moieties. Because the structure elucidation of the naturally occurring product left six stereocenters ambiguous, we implemented bioinformatic analyses, chemical degradation studies and chiral pool fragment synthesis to identify two of the undetermined stereocenters.
View Article and Find Full Text PDFNat Commun
March 2025
Department of Physics, The Ohio State University, Columbus, OH, USA.
We propose a mechanism to explain the emergence of an intermediate gapless spin liquid phase in the antiferromagnetic Kitaev model in an externally applied magnetic field, sandwiched between the well-known gapped chiral spin liquid and the gapped partially polarized phase. We propose that, in moderate fields, π-fluxes nucleate in the ground state and trap Majorana zero modes. As these fluxes proliferate with increasing field, the Majorana zero modes overlap creating an emergent quantum Majorana metallic state with a "Fermi surface" at zero energy.
View Article and Find Full Text PDFLangmuir
March 2025
Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, U.K.
We report the discovery and in-depth investigation of interfacial crystallization (IFC), the assembly and formation of membrane-like crystalline sheets from both chiral amino acid and achiral -substituted glycine "peptoid" amide monomers selectively at vapor-liquid and liquid-liquid interfaces. This is the first assembly process known to be shared by two peptidomimic families of molecules with crucial backbone differences. A series of AFM, SEM, TOF-SIMS, FTIR, X-ray crystallography, counterion screening experiments, QM calculations, and MD simulation studies identified that IFC is based on the assembly of single monomer layers with alternating molecular orientations, which results in bilayers of unit thickness 1.
View Article and Find Full Text PDFSoft Matter
March 2025
University of Bremen, Hybrid Materials Interfaces Group, Faculty of Production Engineering, 28359 Bremen, Germany.
This study investigates the adsorption behaviour of lipase at silica/water and oil/water interfaces by means of molecular dynamics simulations. The findings reveal distinct adsorption orientations and structural differences that can be related to different enzymatic activities and selectivities. At the silica/water interface, lipase adsorbs with the LID region facing the solvent, in a configuration that is not fully open, but still grants access to its catalytic triad, as shown by tunnel calculations.
View Article and Find Full Text PDFJ Chromatogr A
March 2025
Department of pharmacy, Jiangxi University of Chinese Medicine, Nanchang 330004, PR China. Electronic address:
The enantiomeric separation of chiral drugs remains a challenge for the pharmaceutical industry as the pharmacological activities of different isomers may differ, which can cause incalculable secondary effects in the diseases treatment. The highlight of this study is to develop a biphasic recognition chiral extraction (BRCE) platform utilized tartaric acids (TAs) and chiral ionic liquids (CILs) as the synergistic hydrophilic and hydrophobic chiral additives to enhance the extraction performance. The BRCE systems such as organic solvents, type and concentration of chiral additives, initial concentration of equol, extraction temperature, aqueous pH has been systematically investigated.
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