Care for the patient with traumatic brain injury (TBI) in austere or combat environments is challenging because resources are substantially limited as compared with care for these patients in a tertiary medical facility. Significant research has been and will continue to be performed on TBI care in these settings. This includes high-quality, evidence-based guidelines that are routinely updated to help guide the treating team as to best practices for a wide range of TBI presentations, complications, and outcomes. Much less is known regarding best practices for TBI care in a resource-limited environment, such as a facility in an austere environment without advanced imaging, dedicated neurointensive care, or definitive neurosurgical capabilities. The aim of this study was to identify the methodology that will be used for an upcoming in-person guideline conference, focusing on the care of patients with TBI in resource-limited austere and/or combat zones.
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http://dx.doi.org/10.1227/neuprac.0000000000000104 | DOI Listing |
Brain Res
March 2025
Department of Neurosurgery, Jinling Hospital, Jinling School of Clinical Medicine, Nanjing Medical University, Nanjing, China; Department of Neurosurgery, Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China. Electronic address:
Background: Externally caused traumatic brain injury (TBI) poses a woeful worldwide health concern, bringing about disability, death, and prolonged neurological impairment. Increased galectin-3 levels have been linked to unfavorable outcomes in several neurological conditions. This study explores the role of galectin-3 in TBI, specifically examining its contribution to neuroinflammation.
View Article and Find Full Text PDFNeuroimage
March 2025
Department of Psychiatry, Gifu University Graduate School of Medicine, Gifu, Japan.
An auditory steady-state response (ASSR) is an electrophysiological response to periodic stimuli that reflects the synchronization of endogenous oscillations. The 40-Hz ASSR is reduced in patients with schizophrenia, bipolar disorder, and autism spectrum disorder, making it a candidate biomarker for these psychiatric disorders. Previous studies have revealed that experimental conditions such as stimulus duration and inter-stimulus interval tend to affect ASSR, suggesting that novelty detection may play an important role in determining the magnitude of ASSR.
View Article and Find Full Text PDFJ Ethnopharmacol
March 2025
Shenzhen Clinical College of Integrated Chinese and Western Medicine, Guangzhou University of Chinese Medicine; Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen, 518104, P.R.China. Electronic address:
Ethnopharmacological Relevance: Guanxin II, proposed by Chen Keji (National master of traditional Chinese medicine), possesses cerebral-protective effect. Interestingly, its simplified prescription Danshen-Chuanxiong-Honghua (DCH) can also clinically ameliorate cerebral impairment and improve spatial cognitive deficits, similar to original formula's function.
Aim Of The Study: We aimed to elucidate the rationality of DCH's natural existence, qualitatively identify DCH-derived phytochemicals, thereby validate cerebral protective effect, and expose potential mechanism of DCH and its main absorbed compound ferulic acid (FA).
Ann Phys Rehabil Med
March 2025
AP-HP, GH Paris Saclay, Hôpital Raymond Poincaré, service de Médecine Physique et de Réadaptation 104, boulevard Raymond Poincaré, 92380 Garches, France; INSERM DevPsy, CESP, UMR 1018, Université Paris-Saclay, UVSQ, 16 Av. Paul Vaillant Couturier, 94800 Villejuif, France. Electronic address:
Mult Scler Relat Disord
March 2025
Department of Physical Medicine & Rehabilitation, Rutgers - New Jersey Medical School, 183 South Orange Avenue, Suite F-1560, Newark, NJ 07101, USA; Center for Neuropsychology and Neuroscience Research, Kessler Foundation, 120 Eagle Rock Avenue, Suite 100, East Hanover, NJ 07936, USA. Electronic address:
Background: Cognitive impairment and fatigue are two prevalent symptoms of multiple sclerosis (MS). Fatigue is often thought to be associated with slower processing speed. The Symbol Digit Modalities Test (SDMT) is a widely used assessment of processing speed in MS, but it has also been shown to tap into working memory as well.
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