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Parishin A alleviates insomnia by regulating hypothalamic-pituitary-adrenal axis homeostasis and directly targeting orexin receptor OX.
Eur J Pharmacol
March 2025
Center for Pharmaceutical Sciences and Engineering, Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, China. Electronic address:
Parishin A (PA), a bioactive compound derived from Gastrodia elata Blume, has been used as a herbal remedy for insomnia. Nevertheless, the mechanism underlying the effect of PA on promotion of sleep and its potential targets remain to be elucidated. This study aimed to investigate the potential of PA in ameliorating insomnia, probing into its interactions with the orexin receptor 2 (OX), antagonists of which are used clinically for the treatment of sleep disorders.
View Article and Find Full Text PDFExploring the Antibacterial and Antifungal Efficacy of Herbal Plants: An Ayurvedic Research.
J Pharm Bioallied Sci
December 2024
Department of Prosthodontics and Crown and Bridge, Madha Dental College, Chennai, Tamil Nadu, India.
Context: Nature has endowed humanity with a vast repository of remedies that have been use for ages to heal all sorts of ailments.
Aim: To evaluate the antibacterial and antifungal efficacy of three herbal plants (Justicia adhatoda, Glycyrrhiza glabra, and Punica granatum), on three microorganisms (Streptococcus mutans, Staphylococcus aureus, and Candida albicans) that are present in the oral stoma.
Settings And Design: microbial study.
The GC MS Study of One Ayurvedic Formulation, Navayasa Churnam.
J Pharm Bioallied Sci
December 2024
Department of Anatomy, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India.
Background: Navayasa Churnam is an Ayurvedic medicine traditionally used to treat anemia, heart diseases, skin disorders, piles, and jaundice.
Aim: The present study involves GC-MS analysis of Navayasa Churnam, an Ayurvedic medicine traditionally used to treat anemia, heart diseases, skin disorders, piles, and jaundice.
Methods: The Churnam was sourced from a reputable Ayurvedic vendor in Chennai, India, and prepared according to standard protocols.
Cytotoxicity of Dhanwantharaarishtam on hiPSC Cells - An Study.
J Pharm Bioallied Sci
December 2024
Department of Research and Development, Sree Balaji Medical College and Hospital, Chromepet, Chennai, Tamil Nadu, India.
Background: Dhanwantharaarishtam is a traditional Ayurvedic herbal tonic used to improve digestion, promote lactation, and balance the Vata dosha.
Aim: The study investigates the effects of Dhanwantharaarishtam, a traditional Ayurvedic tonic, on cell viability and cytotoxicity in human induced pluripotent stem cell (hiPSC) cultures.
Methods: The impact of Dhanwantharaarishtam on hiPSC cells was analyzed over a 24 hour period.
Principles and Therapeutics of .
J Pharm Bioallied Sci
December 2024
RAK College of Dental Sciences, RAK Medical and Health Sciences University, Ras Al Khaimah, UAE.
Health is defined as a state of complete physical, mental, and social wellbeing, not merely the absence of diseases or infirmity. means selfless sacrifices performed along with sacred sounds, the mantras. The procedure includes offering selected herbal and sacred materials to the fire to obtain an array of benefits such as air purification and release of therapeutic compounds (antibacterial, antiviral, antifungal, antidepression, and anticonvulsant) in the form of aerosol that enriches the atmosphere and soil.
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