Thermal management at the nanoscale offers potential advancements in power-efficient geometrical design; however, both conduction- and convection-based structural optimization have yet to be fully investigated due to dimensional limitations. In this study, we analytically designed a structured configuration within a regime comparable to the mean free path of heat-transferring carriers. The optimally designed nanowire configuration, featuring aligned nanowires with narrow gaps (∼22 nm), was designed based on the analytic calculation. A tailored nanofabrication technique enabled a reliable geometrical parametric study, experimentally validating the proposed theoretical design. Finally, by engineering both conduction heat loss and air molecular interactions in convective heat loss at the nanoscale, we suggest an optimized heater for atmospheric conditions based on scaling factor-induced thermophysical properties, surpassing the efficiency of traditional film-based heaters.
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http://dx.doi.org/10.1039/d4na00894d | DOI Listing |
Arch Dermatol Res
March 2025
Department of Dermatology, Medical Research and Clinical Studies Institute, National Research Centre, Giza, Egypt.
Primary hyperhidrosis (PH) is the presence of increased sweating in the absence of a physiological trigger or underlying identifiable pathological cause. The aim of this study was to assess the impact of primary hyperhidrosis on patients' quality of life in Damietta; one of Egypt's governorates. This cross sectional study included 302 patients aged between 8 and 35 years and fulfilling diagnostic criteria of primary hyperhidrosis.
View Article and Find Full Text PDFEndokrynol Pol
March 2025
Department of Clinical Laboratory, the First Affiliated Hospital of Guangxi Medical University, Key Laboratory of Clinical Laboratory Medicine of Guangxi Department of Education, Nanning, Guangxi, China.
Introduction: Thiamine-responsive megaloblastic anaemia syndrome (TRMA) is a rare genetic disease caused by mutations in the SLC19A2 gene that encodes thiamine transporter 1 (THTR-1). The common manifestations are diabetes, anaemia, and deafness. The pathogenic mechanism has not yet been clarified.
View Article and Find Full Text PDFAnn Afr Med
March 2025
Department of Obstetrics and Gynecology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Background: Preventing postpartum haemorrhage (PPH) is a significant concern because of its effect on maternal morbidity and mortality. PPH is leading cause of maternal death in developing countries and also globally.
Aim: Evaluation of safety and efficacy of carbetocin versus oxytocin for PPH prevention in caesarean deliveries.
Medicine (Baltimore)
March 2025
Department of Anesthesiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Background: Postoperative shivering may lead to severe side effects during postoperative care, particularly in patients with impaired cardiopulmonary function. The efficacy of oral gabapentin as a preventive strategy for postoperative shivering has not been quantitatively analyzed. In this meta-analysis, we aimed to evaluate the effectiveness of gabapentin as a drug for treating postoperative shivering.
View Article and Find Full Text PDFSci Signal
March 2025
National & Local Joint Engineering Research Center of High-Throughput Drug Screening Technology, Hubei University, Wuhan, China.
Brown and beige adipocytes dissipate energy to generate heat through uncoupled respiration, and the hormone norepinephrine plays an important role in stimulating brown fat thermogenesis and beige adipocyte development in white adipose depots. Increasing energy expenditure by promoting the function and development of brown and beige fat is a potential approach to treat obesity and diabetes. Here, we investigated the effects of macrophage sirtuin 6 (SIRT6) on the regulation of the norepinephrine content of brown adipose tissue (BAT) and on obesity in mice.
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