Central neurocytomas are rare, typically benign neuronal tumors that primarily affect young adults and are most commonly located within the lateral ventricles. This report presents the case of a 23-year-old male who presented with a two-month history of progressive headache, nausea, vomiting, and cognitive decline. Neurological examination revealed papilledema, indicative of increased intracranial pressure. Magnetic resonance imaging of the brain demonstrated a well-defined, partially calcified intraventricular lesion with associated obstructive hydrocephalus. Histopathological analysis following a stereotactic biopsy confirmed the diagnosis of central neurocytoma, with immunohistochemistry showing positivity for synaptophysin and neuronal nuclear antigen. The patient underwent a successful gross total resection of the tumor, and postoperative magnetic resonance imaging confirmed complete removal with no residual disease. The patient's recovery was uneventful, and he remains asymptomatic at six months post-surgery with no evidence of recurrence. This case underscores the importance of early recognition, accurate diagnosis, and timely surgical intervention in the management of central neurocytomas. Additionally, it highlights the favorable prognosis associated with gross total resection, although long-term surveillance remains essential to detect any recurrence.
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http://dx.doi.org/10.7759/cureus.77470 | DOI Listing |
Cureus
January 2025
College of Medicine, Jazan University, Jazan, SAU.
Central neurocytomas are rare, typically benign neuronal tumors that primarily affect young adults and are most commonly located within the lateral ventricles. This report presents the case of a 23-year-old male who presented with a two-month history of progressive headache, nausea, vomiting, and cognitive decline. Neurological examination revealed papilledema, indicative of increased intracranial pressure.
View Article and Find Full Text PDFWorld Neurosurg
February 2025
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Objective: The utility of the tubular retractor for deep-seated tumors, including intraventricular tumors, has recently been reported. However, the surgical field's depth and narrowness can lead to blind spots, and it is crucial to prevent damage to the cortex and white matter fibers in eloquent areas. Therefore, preoperative simulation is critical for tubular retractor surgery.
View Article and Find Full Text PDFChilds Nerv Syst
December 2024
Department of Neurosurgery, Sapporo Medical University School of Medicine, Sapporo, Japan.
Extraventricular neurocytoma (EVN) is a rare neuronal tumor with a marked tendency towards ganglionic or glial differentiation. Although EVN commonly occurs in young adults, congenital cases are extremely rare, and standardized therapeutic strategies remain undetermined. The presence of atypical features such as increased mitotic activity on histological analysis is correlated with a higher rate of recurrence and poor prognosis.
View Article and Find Full Text PDFCase Rep Pathol
March 2024
Department of Pathology, School of Medical Sciences, University of Cape Coast, Cape Coast Teaching Hospital, Cape Coast, Ghana.
Front Oncol
September 2024
Department of Neurosurgery, Ji'an Central People's Hospital, Ji'an, China.
We report a case of neurocytoma originating from cranial nerve V. A 53-year-old female patient presented with a 20-day history of right frontotemporal facial paresthesia and pain. Magnetic resonance imaging (MRI) showed a 2.
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