J Orthop Case Rep
Department of Orthopaedics, GSVM Medical College, Kanpur, Uttar Pradesh, India.
Published: February 2025
Introduction: Treatment of supracondylar and intercondylar fractures of the distal femur has historically been difficult. These fractures are often unstable and comminuted and tend to occur in the elderly or in patients with multiple injuries.
Objective: The purpose of the study is to assess the functional and radiological outcome of locking plate fixation in AO type 33C distal femur fractures.
Materials And Methods: A total of 49 patients with distal femoral fractures were operated by open reduction with internal fixation with a distal femur-locking compression plate (LCP) through the standard swashbuckler approach. The functional and radiological outcomes were assessed using the Neers scoring system.
Results: Out of 49 patients, Muller type C2 was the most common fracture with 36 out of 49 (73.5%). Union was found in 47 patients with two patients presenting with non-union. The average union time of the fracture was 12-20 weeks with the mean time of union being 16.2 weeks. All patients were successfully given a walking aid in the 20th week. The average knee score was 79.71 using the Neers scoring system.
Conclusion: Fractures of the distal femur are more common in high-velocity injuries and occur in middle-aged males and old age women. Most fractures were comminuted. LCP appears to be technically an ideal implant for comminuted distal femoral fractures with proper physiotherapy producing excellent results. Knee stiffness was the most common complication.
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http://dx.doi.org/10.13107/jocr.2025.v15.i02.5306 | DOI Listing |
Int J Mol Sci
February 2025
Laboratory of New Techniques of Restoration & Reconstruction, Institute of Traumatology & Orthopedics, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Dysregulated iron metabolism-induced ferroptosis is considered a key pathological mechanism in the development of osteoporosis (OP). G protein-coupled receptor 30 (GPR30, also known as Gper1) is an estrogen-binding receptor that has shown therapeutic benefits in patients with certain degenerative diseases. Moreover, several studies have demonstrated the anti-ferroptotic effects of estrogen receptor activation.
View Article and Find Full Text PDFAnimals (Basel)
February 2025
Department of Veterinary Sciences, University of Messina, Polo Universitario dell'Annunziata, 98168 Messina, ME, Italy.
Limb-sparing techniques for appendicular primary bone tumors are still associated with a high rate of complications. Three-dimensional (3D)-printed patient-specific instruments could reduce these complications. The aim of this study is to describe a limb-sparing surgery using 3D-printed patient-specific guides (PSGs) and an endoprosthesis (PSE) to treat femoral chondrosarcoma in a dog.
View Article and Find Full Text PDFPurpose: Investigate intra- and post-operative complications and revisions following distal femoral and/or high tibial derotational osteotomies to correct rotational malalignments of the lower limb in patients with anterior knee pain (AKP) and/or patellofemoral instability (PFI).
Methods: A literature search was conducted on PubMed, EMBASE and Web of Science (until 30 September 2023), including studies reporting complications, reinterventions and revisions following knee derotational osteotomies. Incidence rates were collected for each level of derotational osteotomy (distal femur, high tibia or double-level).
Cureus
February 2025
Department of Neurophysiotherapy, Ravi Nair Physiotherapy College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Traumatic brachial plexus injury (TBPI) is a serious neurological condition most often resulting from trauma. This condition is among the most debilitating injuries affecting the upper limb. The injury is typically categorized as preganglionic or postganglionic based on the site of trauma, proximal to or distal to the dorsal root ganglion (DRG).
View Article and Find Full Text PDFCureus
February 2025
Orthopaedic Surgery, OhioHealth Grant Medical Center, Columbus, USA.
Purpose: There exists controversy in the treatment of acute distal femur fractures as well as distal femur fracture nonunions. The objective of this study is to determine the clinical benefit of adjunctive medial plate application in the setting of acute distal femur fractures and distal femur fracture nonunions.
Methods: This is a retrospective comparative study at a Level 1 academic trauma center, including 104 patients treated for acute distal femur fractures and 23 patients treated for distal femur nonunions between 2015 and 2019.
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