From 2017 to 2023, 196 dead Korean water deer (Hydropotes inermis argyropus), a common wildlife species in Republic of Korea, were necropsied. In one deer, bovine tuberculosis infection was confirmed through necropsy, histopathologic examination, and microbiologic diagnosis.
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http://dx.doi.org/10.7589/JWD-D-24-00061 | DOI Listing |
Biotechnol Bioeng
April 2025
Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in Western China, Ningxia University, Yinchuan, China.
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is one of the most widespread infectious diseases, with nearly 2 billion people infected globally. We present an innovative approach for the real-time detection of TB antigens Mpt64 and Ag85B using DNA aptamers in combination with a graphene oxide (GO)-assisted optical microfiber super-sensor. The high surface-to-volume ratio and superior properties of the GO layer significantly enhance the microfiber's fixation capabilities.
View Article and Find Full Text PDFPLoS One
March 2025
Animal and Plant Health Agency Sutton Bonington, Sutton Bonington, Loughborough, England.
In the UK and Ireland, the European badger is the main wildlife reservoir for Mycobacterium bovis (M. bovis), the causal agent of bovine tuberculosis (bTB). The ability to diagnose M.
View Article and Find Full Text PDFVet Res Commun
March 2025
Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible (IPADS) (INTA Balcarce- CONICET), RN 226 km 73.5, Balcarce, 7620, Argentina.
Bovine tuberculosis is a chronic disease caused by Mycobacterium bovis which rarely causes a neurologic clinical presentation. Tuberculous meningitis is a common clinical finding in young calves in dairy herds where tuberculosis is endemic, associated with the early consumption of milk from infected cows. We report two simultaneous cases of vestibular syndrome, including loss of balance, circling, tilted head, and strabismus in 12- and 16-month-old Holstein heifers on a dairy farm in Tandil, Buenos Aires province, Argentina, with low tuberculosis prevalence (< 1.
View Article and Find Full Text PDFVaccine
March 2025
Centre of Excellence for Bovine TB, Department of Life Sciences, Aberystwyth University, Carwyn James Building, Penglais Campus, Aberystwyth, Ceredigion SY23 3FD, UK.
The VALIDATE Network brings together scientists addressing vaccine development for neglected infectious diseases caused by intracellular pathogens. In September 2023, the first workshop on One Health approaches to research and capacity building was held in Paarl, South Africa, with a focus on tuberculosis and leishmaniasis. Thirty-two scientists from 15 countries presented and discussed broad topics pertinent to zoonotic diseases, cross-species disease transmission, disease mitigation strategies, inequitable access to medicines and health technologies, and health system challenges in One Health.
View Article and Find Full Text PDFJ Adv Vet Anim Res
December 2024
Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan.
Objectives: Tuberculosis (TB) affects humans and animals regardless of species type, causing huge economic losses and deaths worldwide. However, the mechanisms and risk factors of zoonotic transmission are not well known in Pakistan. The current study aimed to identify the potential risk factors associated with TB in farmers and their animals, particularly exposure to infected animals in Lahore District, Pakistan.
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