Background: Autologous breast reconstruction carries an inherent risk of developing venous thromboembolism (VTE), a complication with potentially severe outcomes. This study evaluated the incidence of VTE events in a large cohort of 502 autologous breast reconstructions, achieved through a standardized surgical, anesthesiologic, and thromboprophylaxis protocol. Our primary aim was to evaluate the effectiveness of this comprehensive approach in preventing VTE events.
Methods: We conducted a retrospective analysis of 370 patients who underwent autologous breast reconstruction between December 2007 and February 2023, employing a uniform surgical and anesthesiology protocol designed around the enhanced recovery after surgery (ERAS) protocol. The incidence of VTE and flap-related complications was documented, alongside an evaluation of the potential risk factors and Caprini scores.
Results: None of the patients in this cohort developed deep vein thrombosis or pulmonary embolism. Hematomas were noted in 5.4% of the cases. The mean Caprini score observed was 6.67, ranging from 3 to 9. Incidences of total and partial flap necrosis were recorded in 7 (1.4%) and 9 (1.8%) cases, respectively. Analysis revealed no significant disparity in the complication rates between patients categorized as being at low risk (Caprini score ≤6), at 5.4%, and those deemed to have the highest risk and super high risk together (Caprini score ≥7), at 3.8%.
Conclusions: Our cohort study is the first, to our knowledge, to demonstrate a zero percent incidence of clinical VTE events following autologous breast reconstruction, attributed to the rigorous application of a standardized surgical, anesthesiology, and thromboprophylaxis protocol. This result highlights the potential of a well-implemented pre- and intra-operative management, combined with the ERAS protocol, to significantly reduce the VTE risk in this group of patients.
Level Of Evidence: IV.
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http://dx.doi.org/10.1016/j.bjps.2025.01.084 | DOI Listing |
Int J Surg
March 2025
Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.
Objective: Persistent postoperative sensory loss significantly limits breast reconstruction following mastectomy. In addition, the absence of sensation profoundly impacts patients' physical well-being and overall quality of life. New surgical techniques involving nerve autograft intercostal nerve elongation have been introduced to neurotize reconstructed breasts.
View Article and Find Full Text PDFJ Reconstr Microsurg
March 2025
Division of Plastic Surgery, Indiana University School of Medicine, Indianapolis, Indiana.
Background: Deep inferior epigastric perforator (DIEP) flap is a common autologous breast reconstruction option. DIEP flap may be performed immediately on the day of mastectomy (immediate DIEP) or at a later date typically following placement of a tissue expander during mastectomy (delayed-immediate DIEP). Preparing internal mammary vessels during microsurgical anastomoses involves prolonged retraction of the breast skin flaps, which can increase tension on acutely ischemic mastectomy skin.
View Article and Find Full Text PDFIntroduction Autologous breast reconstruction using free tissue transfer is widely regarded as the gold standard for oncologic reconstruction due to its reliability and high patient satisfaction. However, it is associated with challenges such as prolonged operative time, extended recovery, and potential complications. This study aims to comprehensively evaluate early and late complications, their impact on length of stay, and readmissions in a retrospective study from a single institution.
View Article and Find Full Text PDFPlast Reconstr Surg Glob Open
March 2025
From the Department of Plastic, Reconstructive and Aesthetic Surgery, Hospital of St. John of God, Paracelsus Medical University, Kajetanerplatz, Salzburg, Austria.
J Plast Reconstr Aesthet Surg
November 2024
Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Electronic address:
Background: The deep inferior epigastric perforator (DIEP) free flap reconstruction is a preferred breast reconstruction technique due to its muscle-sparing approach and patient satisfaction. However, donor-site complications, particularly wound dehiscence, remain a concern. Closed incision negative pressure wound therapy using wound vacuum assisted closure (VAC) systems may reduce these complications by enhancing perfusion and minimizing edema.
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