Background: Older adults make up 33% of all trauma admissions in Australia despite comprising 17% of the population with rates rising faster for older age groups compared to any other age group. A high proportion of older adults admitted to hospital following trauma are frail and have increased rates of hospital acquired complications, resulting in poorer outcomes as well as increased resource utilisation and cost to the healthcare system. Length of Stay (LOS) is an important outcome for hospitals, contributing to resource utilisation and patient flow. This study aimed to determine factors associated with the primary outcome of LOS in older persons admitted with trauma at a major trauma centre as targets for improvement.
Methods: Ethics approval was obtained to collect data on all adult trauma admissions ≥ 1 day in patients aged 65 years and over. Patients were included in the Trauma in older persons (TOPS) database if they otherwise met criteria for the pre-existing trauma registry maintained by the hospital's trauma service. Admissions between January 2022 and January 2023 were included. Univariable negative binomial regression identified variables associated with LOS with p-values ≤ 0.1 which were then included in a multivariable regression model. Significance was taken as p-value ≤ 0.05.
Results: 1250 admissions ≥ 1 day and alive at discharge were included in the primary analysis. The median LOS was 7 (4-13) days. In the multivariable model, delirium (Incidence Rate Ratio (IRR) = 1.41, 95%CI = 1.25-1.59), inpatient fall (IRR = 1.46, 95%CI = 1.15-1.86), pneumonia (IRR = 1.28, 95%CI = 1.08-1.53), thromboembolism (IRR = 1.43, 95%CI = 1.05-1.96), blood transfusion (IRR = 1.34, 95%CI = 1.17-1.53) and unplanned intensive care admission (IRR = 1.52, 95%CI = 1.08-2.14) were all associated with increased LOS. Low fall mechanism was high risk for longer LOS (IRR = 1.26, 95%CI = 1.11-1.43).
Conclusions: After controlling for available factors, inpatient complications and patients admitted following low falls were identified as high risk for increased LOS and may represent areas for targeted quality improvement for older adults admitted following trauma.
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http://dx.doi.org/10.1186/s12877-025-05755-6 | DOI Listing |
Obesity (Silver Spring)
March 2025
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Objective: The objective of this study was to evaluate associations of early-pregnancy plasma per- and polyfluoroalkyl substances (PFAS) with maternal post-pregnancy weight trajectory parameters.
Methods: We studied 1106 Project Viva participants with measures of early-pregnancy plasma concentrations of eight PFAS. We measured weight at in-person visits at 6 months and 3, 7, and 12 years after pregnancy and collected self-reported weight via annual questionnaires up to 17 years after pregnancy.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
October 2024
Department of Prevention and Treatment, Hunan Institute for Tuberculosis Control (Hunan Chest Hospital), Changsha 410013, China.
Objectives: Reducing mortality during anti-tuberculosis treatment is crucial for completing full-course standardized therapy and achieving tuberculosis cure. The study aims to analyze the mortality and its influencing factors among pulmonary tuberculosis patients undergoing anti-tuberculosis treatment in Hunan Province.
Methods: In this retrospective cohort study, data on pulmonary tuberculosis patients from the Hunan Provincial Tuberculosis Management Information System were collected between January 1, 2019 and December 31, 2023.
BMJ Open
March 2025
University of Southern California Keck School of Medicine, Los Angeles, California, USA
Objectives: Extended life expectancy due to treatment improvements has increased the diagnosis of cancer among people living with HIV (PLWH) in Africa. Despite documented impacts of stigma on cancer preventive behaviours and care, little is known about the intersections of cancer and HIV stigma and the effects on prevention and care behaviours for both conditions. This study aims to examine experiences and drivers of cancer stigma and their associations with access to and utilisation of cancer prevention services among PLWH.
View Article and Find Full Text PDFEndocr Pract
March 2025
The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong SAR, China; Centre for Health Education and Health Promotion, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China; Department of Global Health, School of Public Health, Peking University, Beijing, China. Electronic address:
Objectives: Adrenal gland cancer (AGC) is a rare cancer with a poor prognosis. Studies on this cancer have been limited. This study, for the first time, aims to analyse the global disease burden and trends of adrenal gland cancer in country level and examine lifestyle and socioeconomic risk factors to generate hypotheses.
View Article and Find Full Text PDFAm J Clin Nutr
March 2025
Assistance Publique-Hôpitaux de Paris (AP-HP), Department of Gastroenterology, IBD and Intestinal Failure, Beaujon Hospital, Clichy, France. Electronic address:
Background: Home parenteral support (PS) is the standard treatment for chronic intestinal failure (CIF) with short bowel syndrome (SBS) as the leading cause. However, outcomes of PS in older patients remain poorly studied.
Methods: This retrospective observational study evaluated patients newly diagnosed with SBS-CIF initiating PS between 2015 and 2020 at a national French CIF referral center.
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