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The "Opercular" Approach to Orbital Reconstruction after Orbital Exenteration Following Rhino-Orbital-Cerebral Mucormycosis: A Novel Method.
Indian J Plast Surg
February 2025
Department of Oral and Maxillofacial Surgery, Aakar Asha Hospital, Hyderabad, Telangana, India.
Rhino-orbital cutaneous mucormycosis (ROCM) leading to orbital exenteration can be debilitating functionally as well as psychosocially. Orbital reconstruction following exenteration for mucormycosis has centered on volume filling with local, regional, or free flaps. This case series is built on the original idea of a bilayered operculum at the orbital inlet.
View Article and Find Full Text PDFMalignant Peripheral Nerve Sheath Tumor (MPNST) Arising from Orbital Plexiform Neurofibroma in a Small Child With Neurofibromatosis Type 1.
Cancer Diagn Progn
March 2025
Institute of Neuropathology, Eppendorf University Hospital, University of Hamburg, Hamburg, Germany.
Background/aim: Neurofibromatosis type 1 (NF1) is an autosomal dominant hereditary tumor predisposition syndrome. In approximately 30% of cases, plexiform neurofibromas (PNFs) are identified, which are precursor lesions for malignant peripheral nerve sheath tumors (MPNSTs). MPNST is a major cause of the reduced life expectancy of NF1 patients.
View Article and Find Full Text PDFImmunotherapy for orbital squamous cell carcinoma.
Orbit
February 2025
Discipline of Ophthalmology & Visual Sciences, University of Adelaide, Adelaide, SA, Australia.
Purpose: To evaluate the demographics, clinical features and response of orbital squamous cell carcinoma treated with immunotherapy in an Australian and New Zealand cohort.
Methods: This is a multi-institutional, retrospective case series. Data was collected on patient demographics, clinical presentation, imaging findings, treatment course and outcomes.
Long-Term Outcomes After Multidisciplinary Treatment for Pediatric Orbital Rhabdomyosarcoma.
Cancers (Basel)
February 2025
Orbital Center, Department of Ophthalmology, Amsterdam University Medical Centers, 1105 AZ Amsterdam, The Netherlands.
(1) Background: Orbital rhabdomyosarcoma is a rare and aggressive soft tissue tumor that primarily occurs in the eye socket (orbit) of children. Treatment usually involves a combination of surgery, chemotherapy, and radiation therapy, aiming to remove the tumor and prevent metastasis. (2) Methods: An institutional retrospective study was conducted with data from 39 patients with primary orbital RMS treated between 1995 and 2016 at the Amsterdam University Medical Centers/Emma Children Hospital.
View Article and Find Full Text PDFAnterolateral thigh (ALT) flap for facial reconstruction following orbital necrotising fasciitis.
BMJ Case Rep
February 2025
Plastic and Reconstructive Surgery, Royal Free London NHS Foundation Trust, London, UK.
Periorbital necrotising fasciitis is an extremely rare and life-threatening condition, often requiring complex reconstructive strategies. The anterolateral thigh (ALT) flap is a fasciocutaneous flap often employed for cancer and trauma reconstruction. We report the successful utilisation of the ALT flap as a single-stage operation for reconstruction of a large tissue defect following extensive debridement and orbital exenteration using the reconstructive elevator as a framework for decision-making.
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