Introduction: The goal of this report is to highlight an unanticipated effect of medicinal mushroom supplement in reducing seizures in a child.
Methods: A detailed case report and literature review.
Results: Medicinal mushroom extract supplementation resulted in a sustained 98% reduction in seizure frequency three years after initiation.
Discussion: This case report provides details of the child's case and reviews the limited literature related to medicinal mushroom therapy for epilepsy with the intent to stimulate interest in more detailed study of medicinal mushroom compounds for the treatment of treatment-resistant epilepsy.
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| http://dx.doi.org/10.1016/j.pediatrneurol.2025.01.017 | DOI Listing |
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Edible and medicinal mushroom polysaccharides (EMMPs) have been widely studied for their various biological activities. It has been shown that EMMPs could modulate microbiota in the large intestine and improve intestinal health. However, the role of EMMPs in protecting the gastric barrier, regulating gastric microbiota, and improving gastric health cannot be ignored.
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Shanghai Key Laboratory of Diabetes Mellitus, Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.. Electronic address:
The global prevalence of metabolic diseases is on the increase, and it has become a significant threat to the health and lives of individuals. Ergothioneine (EGT) is a natural betaine amino acid found in various foods, particularly mushrooms. EGT cannot be synthesized by mammals; it is absorbed into small intestinal epithelial cells by a cationic protein, the novel organic cation transporter 1 (OCTN1), and transported to certain organs.
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