Multimode fibers have recently attracted significant attention due to their high-power handling capability and beam self-cleaning property that results in a single-mode profile at the fiber output. Here, we perform a detailed experimental comparison of the relative intensity noise (RIN) of all-fiber supercontinuum (SC) generated in multimode step-index (MMF) and graded-index (GRIN) fibers. We also characterize the spatial intensity profile of the SC in different wavelength bands, showing that it is near single mode across the full spectrum. Our results show that the RIN of SC generated in multimode GRIN fibers is not only lower than that generated in a step-index MMF but close to that of a SC generated in a single-mode fiber.
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http://dx.doi.org/10.1364/OL.542354 | DOI Listing |
J Am Coll Cardiol
March 2025
Ciccarone Center for Prevention of Cardiovascular Disease, Johns Hopkins Medicine, Baltimore, Maryland, USA; American Heart Association Tobacco Regulation and Addiction Center, Dallas, Texas, USA. Electronic address:
Background: Cigarette smoking is a strong risk factor for cardiovascular harm.
Objectives: The study sought to explore the detailed relationships between smoking intensity, pack-years, and time since cessation with inflammation, thrombosis, and subclinical atherosclerosis markers of cardiovascular harm.
Methods: We included 182,364 participants (mean age 58.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
October 2024
Department of Laboratory Medicine, Third Xiangya Hospital, Central South University, Changsha 410013, China.
Objectives: () adheres to the surface of medical devices, forming highly drug-resistant biofilms, which has made the development of novel antibacterial agents against and its biofilms a key research focus. By drug repurposing, this study aims to explore the combinational antimicrobial effects between pinaverium bromide (PVB), a -type calcium channel blocker, and oxacillin (OXA) against .
Methods: Clinical isolates of were collected from January to September 2022 at the Department of Clinical Laboratory of the Third Xiangya Hospital, Central South University.
Talanta
March 2025
The Key Laboratory for Biomedical Photonics of MOE at Wuhan National Laboratory for Optoelectronics, Hubei Bioinformatics & Molecular Imaging Key Laboratory, Systems Biology Theme, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China. Electronic address:
The detection of glycosylation alterations is essential for elucidating the roles of glycan functions in biological processes and identifying potential disease biomarkers. Stable isotopic chemical labeling, coupled with mass spectrometry (MS), represents a powerful approach in quantitative glycomics. In this study, we synthesized a novel isotopic hydrazide pair, 2,6-Dimethyl-4-chinolincarbohydrazid (DMQCH) and its deuterium isomer DMQCH-d, via an efficient and cost-effective method, and applied it for the first time in MALDI-MS-based quantitative glycomics.
View Article and Find Full Text PDFTalanta
March 2025
European Commission, Joint Research Centre (JRC), Karlsruhe, Germany.
In this paper we present the high-precision and accurate Th/Th isotope ratio measurement by a novel multi-collector inductively coupled plasma mass spectrometer with a pre-cell mass filter and a MS/MS collision/reaction cell (Neoma™ MC-ICP-MS/MS). No tailing correction is needed for the Th signal, as the tailing of an adjacent high intensity peak (abundance sensitivity) is effectively reduced due to high extent of Ar-based ion removal before the electrostatic analyser/magnetic sector. The obtained abundance sensitivity at m-2 (i.
View Article and Find Full Text PDFAm J Emerg Med
February 2025
Adult Emergency Department - SAMU, Hôpital. Pellegrin, Bordeaux University Hospital INSERM 1219, AHeaD team, Bordeaux Population Health Research Centre, Bordeaux University - ISPED, F-33076 Bordeaux Cedex, France. Electronic address:
Objective: This study aims to assess whether the emotions experienced during an urgent health problem represent risk factors for developing chronic pain.
Method: A pain study was carried out as part of a randomized multicentre study on the prevention of post-concussion syndrome and post-traumatic stress syndrome (SOFTER) following emergency hospitalisation. Nine hundred and fourteen patients not suffering from chronic pain at admission provided information on the presence and intensity of eight emotions (anger, fear, regret, sadness, relief, contentment, joy, and interest) during their stay at the emergency department.
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