Vertigo is a common symptom encountered by neurologists in clinical practice. Position-dependent vertigo can occur at the onset of autoimmune encephalitis, often being misinterpreted as benign paroxysmal positional vertigo (BPPV). This study describes a clinical case of a patient with autoimmune encephalitis associated with GAD65 antibodies, who initially presented with systemic positional vertigo.
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http://dx.doi.org/10.7759/cureus.77355 | DOI Listing |
Cureus
February 2025
Center for General Medicine Education, School of Medicine, Keio University, Tokyo, JPN.
Dizziness is a common chief complaint that often poses a diagnostic challenge. A 79-year-old man was initially misdiagnosed with peripheral vertigo based on normal neuroimaging but later developed altered consciousness and involuntary limb movements, ultimately revealing carbamazepine (CBZ) toxicity. This case highlights a critical diagnostic pitfall: prematurely attributing dizziness to peripheral vertigo without considering drug-induced syndromes.
View Article and Find Full Text PDFOtol Neurotol
April 2025
Department of Postgraduate Studies in Medical Sciences, University of Brasília, Brasília, Federal District, Brazil.
Objective: The study aimed to compare the effectiveness of endoscopic-guided versus microscopic endaural and canal wall up approaches in the resection of middle ear cholesteatoma in both adult and pediatric patients.
Methods: A comprehensive search was conducted in PubMed, Embase, and the Cochrane Central Register of Controlled Trials up to April 2024, covering studies published between 2004 and 2024. Cohort and randomized trials addressing middle ear cholesteatoma resection were included.
Otol Neurotol
April 2025
Department of Otolaryngology-Head & Neck Surgery, Division of Otology & Neurotology, Washington University in St. Louis, St. Louis, Missouri.
Objective: To assess whether postoperative speech recognition after cochlear implantation (CI) differ between age groups of 80 to 89 and 90+.
Study Design: Retrospective cohort study.
Setting: Tertiary academic referral center.
Int J Mol Sci
February 2025
Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
The calcium- and integrin-binding protein (CIB) family, comprising four evolutionarily conserved members (CIB1, CIB2, CIB3, and CIB4), is characterized by canonical EF-hand motifs. The functions of CIBs in the inner ear have been investigated, although further research is still necessary to gain a comprehensive understanding of them. Among the CIB family members, CIB2 is essential for auditory function.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
January 2025
Department of Neuro-Otology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh India.
Unlabelled: In India, 7-8% of the population is affected by post lingual deafness, which can lead to job dissatisfaction, depression, social withdrawal, and educational challenges. Despite the benefits, cochlear implantation in Northern India remains underutilized. This study examines the impact of cochlear implants on post lingual deafness, along with their etiology and indications.
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