Prenatal Diagnosis and Classification of Type I Persistent Left Superior Vena Cava.

J Ultrasound Med

Department of Ultrasound Diagnosis, Wuwei People's Hospital, Wuwei, People's Republic of China.

Published: February 2025

Objective: This study aimed to assess the utility of two-dimensional (2D) ultrasonography in diagnosing and classifying fetal type I persistent left superior vena cava (PLSVC).

Methods: The diameter (D) of the coronary sinus (CS) was measured in the four-chamber view and the diameter (D) of the PLSVC was measured in the three-vessel trachea view; the ratio of the diameter of CS to PLSVC (D/D) and the ratio of gestational week (GA)/D and GA/D were calculated to analyze the correlation between measurement and classification of type I PLSVC.

Results: Compared the parameter of Ia and Ib Group, the differences in D, D, GA/D, and GA/D were statistically significant (P < .05). D and D are independent factors for the differential diagnosis of type I PLSVC, with odds ratios (OR) of 5.397 and 2.661, respectively, and both are statistically significant (P < .05). The nomogram model exhibited superior performance in diagnosing type I PLSVC, with the highest AUC value of 0.853, a sensitivity of 96.55%, and a specificity of 66.25%.

Conclusion: The combination of D, D, GA/D, and GA/D is valuable for diagnosing and classifying fetal type I PLSVC, demonstrating significant clinical application value.

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http://dx.doi.org/10.1002/jum.16663DOI Listing

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