Myelomeningocele is a complex congenital defect that affects the spinal cord and structures associated with it. These patients often have neurogenic bowel and bladder dysfunction with constipation, fecal and urinary incontinence. In addition to dietary modifications, laxatives, and enemas, therapies such as biofeedback and neurostimulation (invasive and noninvasive) are sometimes used. These techniques are rarely available, may require surgical procedures, and are not devoid of complications. We present the case of a 13-year-old boy with myelomeningocele at the L4 level, with constipation, dyssynergic defecation, and fecal incontinence (FI). He was treated with biofeedback achieving partial improvement of FI, and then with transcutaneous electrical neurostimulation (TENS) with subsequent resolution of constipation and FI. To our knowledge, this is the first case report using neurostimulation with TENS applied to the S2-S4 dermatomes in a patient with myelomeningocele. This represents a safe, noninvasive, and low-cost treatment for these patients.
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http://dx.doi.org/10.1002/jpr3.12152 | DOI Listing |
Cureus
February 2025
Pediatric Anesthesiology, Hospital Infantil de México, Federico Gómez, Mexico City, MEX.
Giant encephalocele is a rare pediatric surgical entity that poses unique challenges. Few cases have been reported in the medical literature, and its cause is unknown. Factors that increase the likelihood of developing this pathology are radiation, infections, hyperinsulinemia, vitamin deficiencies related to neural tube closure defects, maternal smoking, alcohol, and anticonvulsants.
View Article and Find Full Text PDFWorld Neurosurg
March 2025
Department of Children Neurosurgery, Jagiellonian University Medical College, Kraków Poland.
Purpose: Chiari malformation type 2 (CMII) is a herniation of anatomical structures of the posterior fossa due to myelomeningocele (MMC), the most common neural tube defect. Most patients with MMC exhibit radiological signs of CMII. The study aimed to evaluate radiological parameters of the posterior fossa in patients undergoing surgery for CMII, with the goal of establishing structural indications for surgical treatment to prevent clinical manifestations and life-threatening symptoms.
View Article and Find Full Text PDFChildren (Basel)
February 2025
Division of Pediatric Gastroenterology, Hepatology and Nutrition, Cardinal Glennon Children's Medical Center, Saint Louis University School of Medicine, St. Louis, MO 63104, USA.
Background/objectives: Patients with spina bifida (SB) commonly experience neurogenic bowel dysfunction, characterized by defecation-related symptoms. While anorectal dysfunction and slow transit constipation (STC) have been implicated, the role of colonic motility in SB remains unclear. This study aimed to evaluate colonic motility in SB patients with refractory bowel dysfunction.
View Article and Find Full Text PDFChilds Nerv Syst
February 2025
Division of Neuropediatrics, Department for Children'S and Adolescence Health, University Hospital Leipzig, Leipzig, Germany.
Introduction: The management of open neural tube defects (ONTD) has significantly improved with fetal surgery, but many children remain ineligible for fetal therapy. This study assesses the impact of intraoperative neurophysiological monitoring (IONM) during postnatal myelomeningocele (MMC) repair and its potential to optimize functional outcomes.
Patients And Methods: Seven newborns with thoracolumbar or lumbar MMC underwent postnatal surgical repair using IONM.
Birth Defects Res
February 2025
Department of Maternal-Fetal Medicine, Instituto Nacional de Perinatologia, Mexico City, Mexico.
Background: Neural tube defects (NTDs) are the second most common congenital malformation. Periconceptional, prenatal, and perinatal interventions have been implemented to reduce their incidence and improve those affected's survival and quality of life. The study aims to describe this population's prevalence, interventions performed, clinical management, and perinatal outcomes.
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