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Clinical Presentations and Characteristics of NSAIDs Hypersensitivity in a Tertiary Care Hospital in Indonesia: A Case Series.
Int Med Case Rep J
January 2025
Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, 40132, Indonesia.
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely administered in all age groups due to their effectiveness in reducing fever, relieving pain, and reducing inflammation. However, they have also been identified as the second most common cause of drug-induced hypersensitivity reactions, after beta-lactam antibiotics. Adverse reactions to NSAIDs can range from expected pharmacological side effects such as gastritis to severe allergies, including anaphylaxis.
View Article and Find Full Text PDFRelationship between cigarette smoking and chronic spontaneous urticaria. Is there a difference in neutrophil-lymphocyte ratio?
Postepy Dermatol Alergol
December 2024
Department of Internal Medicine, Allergology, Endocrinology and Gastroenterology, University Hospital, Opole, Poland.
Introduction: Chronic spontaneous urticaria (CSU) is defined as the appearance of itchy wheals and/or angioedema for at least 6 weeks. Cigarette smoking is one of the world's most common addictions. It is a cause of serious diseases such as renal cancer or thromboembolic incidents.
View Article and Find Full Text PDFCharacteristics of Patients with Hereditary Angioedema Who Reduced Lanadelumab Treatment Administration Frequency: A Retrospective Observational Study of US Claims Data.
Drugs Real World Outcomes
January 2025
Takeda Pharmaceuticals USA, Inc., 45 Hayden Avenue, Lexington, MA, 02421, USA.
Background: Lanadelumab is the only long-term prophylaxis indicated for reduced administration frequency in patients with hereditary angioedema who have been well controlled for > 6 months. Understanding the characteristics of patients who reduce administration frequency will help identify populations where frequency modifications may be appropriate.
Objective: We aimed to describe characteristics of patients who did and did not reduce lanadelumab administration frequency to inform real-world dosing regimens, and characteristics indicative of sustained frequency reduction.
Assessing Preferences of Patients with Chronic Spontaneous Urticaria for Injectable Treatment Profiles.
Patient
January 2025
Division of Rheumatology, Allergy and Immunology, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Background: In the context of injectable biologic products approved or in development for chronic spontaneous urticaria (CSU), it is important to capture which treatment attributes matter most to patient and what trade-offs patients are willing to make.
Objectives: The CHOICE-CSU study aimed to quantify patient preferences toward injectable treatment attributes among patients with CSU, inadequately controlled by H1-antihistamines.
Methods: This was a two-phase cross-sectional patient preference study in adult patients with a diagnosis of CSU, inadequately controlled by H1-antihistamines.
Beyond Skin Deep: Olfactory Dysfunction as a Common Problem Among Chinese Hereditary Angioedema Patients.
Clin Exp Allergy
January 2025
Division of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, SAR, China.
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