: The lack of new antimicrobial drugs and increased antimicrobial resistance has focused attention on the employment of essential oils (EOs) in human and veterinary medicine. The aim of this study was to test new binary associations between known and uncommon EOs. : EOs from L., L., L., L. var. were tested individually and in binary combinations to study, as follows: antibacterial activity against , including methicillin-resistant (MRSA) and ; antioxidant capacity via redox-based assays (DPPH, ABTS and FRAP); and anti-inflammatory activity via the bovine serum albumin denaturation inhibition assay. L. showed good antibacterial activity against all strains (MIC = 0.03-0.12%, /), followed by L., and also had the best antioxidant and anti-inflammatory activities. Synergistic and additive effects were observed for the EO combinations L./ L. and L./ L. against and MRSA, respectively. A reduction in biofilm was noted. Antioxidant and anti-inflammatory activities were also detected. : The results suggest that EO combinations may be a promising strategy in veterinary settings for the treatment of infectious diseases caused by , including drug-resistant and biofilm-forming strains accompanied by oxidative stress and inflammation.
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| http://dx.doi.org/10.3390/molecules30030438 | DOI Listing |
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