Acquired immune deficiency syndrome (AIDS) is still a serious public health problem worldwide. This consensus was organized by the Grassroots Inspection Technology Standardization Branch of China International Exchange and Promotive Association for Medical and Health Care, which generated by the national experts in AIDS related testing, public health and infectious diseases after three meetings. In the process of consensus formulation, experts combined the latest human immunodeficiency virus (HIV) related guidelines and research at home and abroad, and ensured the scientific and practical nature of the consensus through literature review, expert discussion, evidence grading, and consensus formation methods and processes. It mainly elaborates on the testing technology and updated standards for HIV infection, diagnosis and prevention strategies for HIV infection, recommendations for key populations to receive HIV infection testing, as well as the challenges and development directions faced by HIV infection testing. It aims to achieve the goal of ending the global AIDS epidemic by 2030, promote HIV screening, early diagnosis and early treatment of key groups as soon as possible, provide medical workers with scientific and normative guidance, improve the detection rate, diagnostic accuracy and management level of HIV infection, so as to improve the quality of life and prognosis of patients, promote the development of public health, and ultimately achieve effective HIV suppression.
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http://dx.doi.org/10.3760/cma.j.cn112150-20241014-00813 | DOI Listing |
Biosaf Health
October 2024
NHC Key Laboratory of Biosafety, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), Research Unit of Adaptive Evolution and Control of Emerging Viruses, Chinese Academy of Medical Sciences, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Biosafety hazards can trigger a host immune response after infection, invasion, or contact with the host. Whether infection with a microorganism results in disease or biosafety concerns depends to a large extent on the immune status of the population. Therefore, it is essential to investigate the immunological characteristics of the host and the mechanisms of biological threats and agents to protect the host more effectively.
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June 2024
Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.
Mpox is a zoonotic infectious disease caused by the mpox virus (MPXV). Historically, the majority of mpox cases have been documented in Central Africa. However, since May 2022, there has been a notable rise in reported cases from regions beyond Africa.
View Article and Find Full Text PDFBiosaf Health
June 2024
Beijing Key Laboratory for HIV/AIDS Research, Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.
The high morbidity and mortality rate of individuals with human immunodeficiency virus (HIV) / acquired immunodeficiency syndrome (AIDS) coinfected with (MTB) is a tough challenge for current global tuberculosis prevention and control efforts. HIV/MTB coinfection is more complex than a single infection, and the interaction between the two diseases aggravates the deterioration caused by the disease, resulting in increased hospitalizations and deaths. Rapid screening and early diagnosis facilitate the timely initiation of anti-tuberculosis treatment in HIV/MTB coinfected individuals, thereby reducing transmission and the incidence of adverse prognoses.
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August 2024
Postgraduate Union Training Base of Jinzhou Medical University, PLA Rocket Force Characteristic Medical Center, Beijing 100088, China.
Integrase strand transfer inhibitors (INSTIs) have emerged as the first-line choice for treating human immunodeficiency virus (HIV) infection due to their superior efficacy and safety. However, the impact of INSTIs on the development of neuropsychiatric conditions in people living with HIV (PLWH) is not fully understood due to limited data. In this study, we conducted a cross-sectional examination of PLWH receiving antiretroviral therapy, with a specific focus on HIV-positive men who have sex with men (MSM) on INSTI-based regimens (n = 61) and efavirenz (EFV)-based regimens (n = 28).
View Article and Find Full Text PDFNutrients
March 2025
Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
: Individuals with HIV on combined antiretroviral therapy (ART) with virologic suppression exhibit chronic immune activation and immune dysfunction. Numerous studies have shown that human milk oligosaccharide (HMO) controls the postnatal transmission of HIV-1, but its effect on adult HIV-1 infection is not known. The purpose of this study was to investigate the anti-HIV activity of Lacto-N-fucopentaose III (LNFPIII) in adult blood-borne macrophages.
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