Purpose: Accelerated Collagen Crosslinking (A-CXL) is widely used worldwide as an effective treatment for keratoconus due to its efficiency and rapidity. This paper aims to identify relevant changes in visual acuity parameters and topographic measurements before and six months after treatment.
Methods: A total of 30 eyes from 20 patients who underwent A-CXL between May 2021 and June 2023 and had at least six months of follow-up were analyzed retrospectively. Comparisons between uncorrected visual acuity, best corrected visual acuity, spherical and cylinder diopters, and topographic measurements like Kmax, SIf, SIb, KVf, KVb, BCVf, BCVb, TCT, and CCT were made before and six months after surgery.
Results: After the accelerated Collagen crosslinking (A-CXL), BCVA improved, cylinder diopters and Kmax values were reduced, and central corneal thickness (CCT) and thinnest corneal thickness (TCT) were elevated.
Discussion: The study has shown results comparable with other studies regarding the heterogeneity of the group study, good outcomes in measuring the corneal central thickness and thinnest corneal thickness, and good evolution of the refraction and visual acuity. Regarding the specific topography markers, like SIf/SIb, KVf/KVb, BCVf/BCVb, and K, minor differences were observed at 6 months follow-up and were not considered statistically relevant. Other studies show a better correlation at 1-year check-ups and similar results at 6-month follow-ups.
Conclusion: This method's main benefits are its brief duration and minimum intrusion, improvement of visual acuity, and the possibility of reintervention for better outcomes.
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http://dx.doi.org/10.22336/rjo.2024.77 | DOI Listing |
Semin Ophthalmol
March 2025
Department of Ophthalmology, Peking University People's Hospital, Beijing, China.
Purpose: To evaluate and contrast the effectiveness and safety of two conbercept treatment protocols-a three-dose treat-and-extend (3+T&E) regimen and a three-dose pro re nata (3+PRN) regimen-in Chinese patients diagnosed with neovascular age-related macular degeneration (nAMD).
Methods: Eligible patients, who had not undergone anti-VEGF intraocular injections within 3 months prior to enrollment, were randomly assigned to either the 3+T&E or 3+PRN regimen. The 3+T&E group received at least three monthly injections, with subsequent visit intervals extended based on disease activity assessment.
J Surg Case Rep
March 2025
Faculty of Medicine, University of Aleppo, Aleppo, Syria.
In endemic regions, intra-orbital hydatid cysts are a rare manifestation of Echinococcus granulosus infection, classically disturbing the liver and lungs. This report details a patient's case with an intra-orbital cyst presenting. Diagnostic imaging revealed a cystic lesion causing optic nerve displacement.
View Article and Find Full Text PDFFront Bioeng Biotechnol
February 2025
Aragon Institute of Research Engineering (I3A), Universidad de Zaragoza, Zaragoza, Spain.
Introduction: Laser refractive surgeries are a safe option for low-to-moderate refractive corrections, providing excellent visual outcomes. Over the years, various procedures have been introduced into clinical practice, but the most performed today remain Photorefractive Keratectomy (PRK), Laser Keratomileusis (LASIK), and Small Incision Lenticule Extraction (SMILE). Although laser refractive treatments are considered safe, clinicians have focused on the risk of post-surgical ectasia, a rare but serious complication.
View Article and Find Full Text PDFFront Med (Lausanne)
February 2025
Department of Cataract Surgery, Oftalvist Alicante, Alicante, Spain.
Background: To evaluate refractive, visual, and patient-reported outcomes three months after bilateral implantation of a novel bi-aspheric, non-diffractive extended depth of focus (EDOF) intraocular lens (IOL) using PhaseRing technology to achieve good vision across distances with reduced dysphotopsia.
Methods: Twenty-two patients received bilateral Asqelio EDOF IOLs (AST VisionCare Inc.) and were evaluated 3 months post-surgery.
Nutrients
February 2025
Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
: The objective of this study was to analyze the relationships between diet and geographic atrophy (GA) progression, both area-based and proximity-based, for dietary pattern, components, and micronutrients. : In the Age-Related Eye Diseases Study (AREDS) and AREDS2, an Alternative Mediterranean Diet Index (aMedi), its nine components, and individual micronutrient intakes were calculated. Mixed-model regression was performed for square root GA area, GA foveal proximity, and acuity.
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