We report a problematic case of solitary fibrous tumor of the orbit in an anemic patient who presented with painless, progressive outward protrusion of the right eye. Magnetic resonance imaging (MRI) orbit and brain with contrast showed a well-defined intraconal lesion in the superomedial aspect of the right orbit. The lesion was excised using a vertical eyelid split orbitotomy with minimal blood loss. Histopathological and immunohistochemical examination showed the features of a solitary fibrous tumor. This case highlighted that with careful surgical planning, total removal of a large vascular tumor could be done with less bleeding, especially in an anemic patient in whom an iota of hemorrhage was life-threatening.
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http://dx.doi.org/10.22336/rjo.2024.82 | DOI Listing |
Int J Gynecol Pathol
March 2025
Emory University Hospital, Atlanta, GA.
Cellular angiofibromas (CAFs) are benign mesenchymal neoplasms of the vulva and lower genitourinary tract. Although most cases are benign with excellent prognosis, data on CAFs with cytologic atypia (aCAF) and sarcomatous transformation (tCAF) is limited. We identified 13 vulvar CAFs comprising 4 aCAFs and 9 tCAFs.
View Article and Find Full Text PDFCureus
February 2025
Thoracic Surgery, Mohammed VI University Hospital, Marrakesh, MAR.
Solitary fibrous tumor of the pleura (SFTP) is a rare mesenchymal tumor, making up a small fraction of primary pleural tumors. It is typically benign but can display malignant features. This case presents a 59-year-old patient with a giant malignant SFTP located in the right posterior inferior mediastinum, which caused significant compression of adjacent structures, including the lung, heart, and esophagus.
View Article and Find Full Text PDFJ Nucl Med
March 2025
Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore;
Solitary fibrous tumor (SFT) is a rare sarcoma of mesenchymal origin. Although generally benign, SFTs carry the risk of recurrence and metastasis, with limited effective treatment options. The aims of this study are to compare the performance of fibroblast activation protein inhibitor (FAPI), [Ga]Ga-DOTA-FAPI-04 (denoted as [Ga]Ga-FAPI-04), and conventional [F]FDG PET/CT in patients with recurrent or metastatic SFTs head to head and to preliminarily explore the value of FAP-targeted radiopharmaceutical therapy with Lu for SFT patients.
View Article and Find Full Text PDFJ Oral Biol Craniofac Res
February 2025
Department of Oral and Maxillofacial Surgery, Post Graduate Institute of Dental Sciences, Rohtak, 124001, Haryana, India.
Solitary fibrous tumor (SFT) is a rare, benign spindle-cell neoplasm initially thought to be of mesothelial origin but later recognized as mesenchymal. While uncommon in the head and neck region, SFTs typically present in the oral cavity, orbit, and paranasal sinuses. The tumor's imaging characteristics, such as those seen in ultrasound and MRI, can often mimic vascular lesions, leading to diagnostic challenges.
View Article and Find Full Text PDFMed Ultrason
March 2025
Department of Ultrasound, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.
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