Geographic variation in abundance and diversity of bacteriophages.

Front Microbiol

Laboratorio de Biología Computacional y Virómica Integrativa, Centro de Investigación en Dinámica Celular, Universidad Autónoma del Estado de Morelos, Cuernavaca, Mexico.

Published: January 2025

Introduction: Prophages play a crucial role in the genomic diversity of , contributing to its pathogenicity and adaptation.

Methods: In this study, we induced and sequenced seven prophages from five isolates of . These were analyzed with 967 prophages identified from various isolates worldwide, plus 21 genomes of other phages infecting previously reported in NCBI. To have an overview of the populations of the prophages infecting .

Results: Our analysis revealed 13 major prophage clusters within the analyzed isolates. Notably, prophages belonging to the genus were the most prevalent. Specifically, -related phages were frequently identified in isolates from Thailand, Mexico, China, and South Korea, which show the geographic prevalence of prophages.

Discussion: This study highlights the importance of considering geographic factors to fully understand prophage diversity and their significant role in the evolutionary dynamics of .

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11813220PMC
http://dx.doi.org/10.3389/fmicb.2025.1522711DOI Listing

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