Recent developments on deep learning established some theoretical properties of deep neural networks estimators. However, most of the existing works on this topic are restricted to bounded loss functions or (sub)-Gaussian or bounded variables. This paper considers robust deep learning from weakly dependent observations, with unbounded loss function and unbounded output. It is only assumed that the output variable has a finite r order moment, with r>1. Non asymptotic bounds for the expected excess risk of the deep neural network estimator are established under strong mixing, and ψ-weak dependence assumptions on the observations. We derive a relationship between these bounds and r, and when the data have moments of any order, the convergence rate is close to some well-known results. When the target predictor belongs to the class of Hölder smooth functions with sufficiently large smoothness index, the rate of the expected excess risk for exponentially strongly mixing data is close to that obtained with i.i.d. samples. Application to robust nonparametric regression and robust nonparametric autoregression are considered. The simulation study for models with heavy-tailed errors shows that, robust estimators with absolute loss and Huber loss function outperform the least squares method.
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http://dx.doi.org/10.1016/j.neunet.2025.107227 | DOI Listing |
ACS Nano
March 2025
School of Chemical Science and Engineering, Tongji University, 1239 Siping Road, Shanghai 200092, China.
The self-assemblies of topological complex block copolymers, especially the AB type miktoarm star ones, are fascinating topics in the soft matter field, which represent typical self-assembly behaviors analogous to those of biological membranes. However, their diverse topological asymmetries and versatile spontaneous curvatures result in rather complex phase separations that deviate significantly from the common mechanisms. Thus, numerous trial-and-error experiments with tremendous parameter space and intricate relationships are needed to study their assemblies.
View Article and Find Full Text PDFPlant Biotechnol J
March 2025
National Key Laboratory of Crop Genetic Improvement and National Center of Plant Gene Research (Wuhan), Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, China.
The dissection of genetic architecture for rice root system is largely dependent on phenotyping techniques, and high-throughput root phenotyping poses a great challenge. In this study, we established a cost-effective root phenotyping platform capable of analysing 1680 root samples within 2 h. To efficiently process a large number of root images, we developed the root phenotyping toolbox (RPT) with an enhanced SegFormer algorithm and used it for root segmentation and root phenotypic traits.
View Article and Find Full Text PDFGastroenterology
March 2025
APC Microbiome Ireland, College of Medicine and Health, University College Cork, Cork, Ireland.
Inflammatory bowel disease (IBD) is marked by significant clinical heterogeneity, posing challenges for accurate diagnosis and personalized treatment strategies. Conventional approaches, such as endoscopy and histology, often fail to adequately and accurately predict medium and long-term outcomes, leading to suboptimal patient management. Artificial intelligence (AI) is emerging as a transformative force enabling standardized, accurate, and timely disease assessment and outcome prediction, including therapeutic response.
View Article and Find Full Text PDFArtif Intell Med
March 2025
Department of Advanced Computing Sciences, Maastricht University, The Netherlands. Electronic address:
Electrocardiographic imaging (ECGI) aims to noninvasively estimate heart surface potentials starting from body surface potentials. This is classically based on geometric information on the torso and the heart from imaging, which complicates clinical application. In this study, we aim to develop a deep learning framework to estimate heart surface potentials solely from body surface potentials, enabling wider clinical use.
View Article and Find Full Text PDFComput Biol Chem
March 2025
Scientific Research Management Department, Shanghai University, Shanghai, 200444, China. Electronic address:
Drug-target affinity prediction is a fundamental task in the field of drug discovery. Extracting and integrating structural information from proteins effectively is crucial to enhance the accuracy and generalization of prediction, which remains a substantial challenge. This paper proposes a pocket-based multimodal deep learning model named PocketDTA for drug-target affinity prediction, based on the principle of "structure determines function".
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