Purpose: To describe a case of presumed MMC-induced retinal toxicity following combined cataract and Xen gel stent surgery.
Methods: Observational case report.
Results: A 66-year-old male presents with progressive vision loss (20/25 baseline to light-perception (LP)) following combined cataract and Xen gel stent surgery in the left eye. The patient received 0.15 ml of 0.4 mg/ml of MMC via intra-tenon injection during the surgery. The patient reported severe eye pain following surgery which gradually resolved over time. Upon examination at post-operative day 41, vessel attenuation, sclerotic vessels, and optic nerve pallor are observed without any retinal hemorrhaging. At post-operative day 55, visual acuity remains at LP with a flat line electroretinogram. Outcomes remain consistent at postoperative day 125.
Conclusion: Care should be taken to avoid intraocular MMC, especially when administered via intra-tenon injection during combined cataract and Xen gel stent surgery.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/ICB.0000000000001729 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Two-Year Outcomes of Phacoemulsification Combined with GATT Versus Standalone GATT in Open-Angle Glaucoma: A Comparative Study.
Diagnostics (Basel)
February 2025
Department of Ophthalmology, Kastamonu University, Kastamonu 37150, Turkey.
: The aim of this paper was to evaluate the two-year outcomes of phacoemulsification combined with gonioscopy-assisted transluminal trabeculotomy (PHACO-GATT) versus standalone GATT in terms of efficacy, safety, and surgical success. : This retrospective, comparative study included 64 eyes of 64 patients with moderate-to-severe open-angle glaucoma: 35 patients (54.7%) with primary open-angle glaucoma (POAG) and 29 patients (45.
View Article and Find Full Text PDFComparison between Phacoemulsification-iStent Inject W and Phacoemulsification-Micropulse Transscleral Laser Therapy in Asian Eyes with Mild-Moderate Open Angle Glaucoma.
J Glaucoma
March 2025
Department of Ophthalmology, National University Hospital, National University Health System.
Prcis: In this retrospective cohort study, the 1-year cumulative probability of failure was comparable, achieving 52.20% in the phacoemulsification-iStent inject W (phaco/iStent) group and 47.80% in the phacoemulsification-micropulse transscleral laser therapy (phaco/MPTLT) group (P=0.
View Article and Find Full Text PDFOne-Year Outcomes of Gonio Scratch as a Minimally Invasive Glaucoma Surgery with Cataract Removal.
J Glaucoma
March 2025
Department of Ophthalmology and Visual Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
Prcis: This study evaluated the 1-year efficacy and safety of a novel minimally invasive glaucoma surgery, gonio scratch, in reducing intraocular pressure of eyes with open-angle glaucoma and cataracts.
Purpose: To evaluate the 1-year efficacy and safety of phacoemulsification cataract extraction combined with gonio scratch (GS-Phaco), a novel minimally invasive glaucoma surgery, in patients with open-angle glaucoma and cataracts.
Patients And Methods: This prospective multicenter clinical trial was conducted at Hiroshima University, Yokoyama Retina Clinic, Kusatsu Eye Clinic, and Miyoshi Eye Clinic in Japan.
XEN 63 in a case of refractory glaucoma secondary to microphthalmia and aphakia.
Arch Soc Esp Oftalmol (Engl Ed)
March 2025
Department of Glaucoma, Institut Clínic d'Oftalmologia (ICOF), Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, Spain.
Microphthalmia (MO) predisposes to glaucoma and congenital cataracts (CC). Cataract removal in MO is characterized by several complications such as aphakic glaucoma (AG). We report the case of a 33-year-old male with MO, aphakia, and refractory glaucoma who underwent inferonasal ab-interno XEN 63 implantation, after posterior vitrectomy.
View Article and Find Full Text PDFReal-world comparison of efficacy and safety of XEN45 implant with phacoemulsification versus iStent inject® W with phacoemulsification.
J Fr Ophtalmol
March 2025
Department of Ophthalmology, Hospital General Universitario Dr. Balmis, Alicante, Spain; Clínica Oftalvist, Alicante, Spain; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain.
Purpose: To compare iStent inject® W+phacoemulsification with XEN45 implant+phacoemulsification over 12 months in mild to moderate glaucoma patients needing cataract surgery at the Hospital General Universitario Dr. Balmis, Alicante, Spain.
Methods: Retrospective clinical cohort study.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!