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J Am Acad Dermatol
November 2024
Department of Dermatology, Weill Cornell Medicine, New York, New York. Electronic address:
Nail unit verruca is the most common nail tumor encountered in clinical practice and may be highly distressing to patients due to reduced functionality, cosmesis, and stigmatization. Subungual and periungual verrucae present a challenge for treatment compared to cutaneous warts of other sites and recurrence rates are high. The risk of spread to other skin and mucosal areas inherent to all warts may be increased given location on the fingertips.
View Article and Find Full Text PDFJAAD Case Rep
November 2024
Division of Dermatology, University of Texas Health San Antonio, San Antonio, Texas.
J Cutan Pathol
September 2024
Dermatology Department, Saint-Pierre and Brugmann University Hospitals-Université Libre de Bruxelles, Brussels, Belgium.
Background: Nail squamous cell carcinoma (NSCC) is the most frequent ungual malignant tumor, but its incidence remains low. The histopathological description is sparse. We aim to characterize NSCC histopathological aspects, search for a correlation with clinical subtypes, and investigate immunohistochemistry expression of p16, p53, and Ki67.
View Article and Find Full Text PDFDermatol Reports
March 2024
Division of Plastic and Reconstructive Surgery, Department of Surgery, Yale School of Medicine, New Haven, CT.
Subungual or periungual cutaneous warts are caused by the human papillomavirus (HPV). These lesions can be refractory to destructive therapy, necessitating the use of intralesional immunotherapies such as antigen. In this case report, we present a 23-year-old female who sustained distal fingertip soft tissue necrosis following intralesional injection of antigen for the treatment of a refractory subungual wart.
View Article and Find Full Text PDFSkin Appendage Disord
April 2024
Department of Dermatology, Weill Cornell Medicine, New York, NY, USA.
Background: Vitamins have gained popularity among physicians and patients for purported benefits to hair, skin, and nail health. Safe and efficacious therapies for nail disorders, many of which are chronic conditions, are needed.
Summary: We conducted a literature review of studies assessing the efficacy of oral, topical, and intralesional vitamin/vitamin derivatives for the treatment of nail disorders, including yellow nail syndrome, brittle nail syndrome, onychomycosis, habit-tic nail deformity, periungual/subungual verruca, and nail psoriasis.
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