Background: This study aimed to examine the iodine concentration in the food items consumed by mothers participating in neonatal screening programs in both areas of the Vidarbha region. A developing fetus relies on a consistent supply of iodine for proper brain and body development. During pregnancy, only the mother can provide the necessary iodine levels. If the mother is iodine-deficient, the child will also lack this essential nutrient. Severe deficiency in the mother can lead to significant stunting of the child's brain and body, potentially preventing normal walking, talking, or cognitive function. Even if the mother's deficiency is mild, the child can still be adversely affected, even if they appear healthy at first glance. The detrimental effects on brain development may manifest later in life as poor academic performance and difficulties in managing daily tasks.
Material And Method: The present cross-sectional research will be performed in collaboration with the Departments of Biochemistry, Obstetrics and Gynecology, Community Medicine, and Pediatrics at Jawaharlal Nehru Medical College Sawangi (Meghe) Wardha, along with Datta Meghe Institute of Medical Science (Deemed University) in Maharashtra, India. Mothers who gave birth agreed to participate by providing written consent for the study.
Results: The average iodine concentrations are quite similar across all sources, though hand pumps show slightly more variability. Different staple foods contain varying levels of iodine, with some foods (like pulses) exhibiting a lot of variation, while others (like rice and potatoes) are more consistent in their iodine content.
Conclusion: The current study is a hospital-based investigation aimed at screening neonates for congenital hypothyroidism (CH) and does not reflect the broader population. To identify CH, screening of neonates will be conducted within the study area, providing a representative view of the condition. The clinical and pathological effects of CH are subtle and often remain unnoticed. Our findings suggest that the prevalence of iodine reflects dietary quality, educational background, and socioeconomic status, all of which can influence growth and development. There are various factors contributing to CH and inadequate fetal growth beyond low iodine levels, which can disrupt thyroid function. The study indicates that iodine levels are indicative of dietary quality as well as educational and social statuses, potentially impacting growth and development through both dietary deficiencies and other factors.
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http://dx.doi.org/10.4103/jpbs.jpbs_1394_24 | DOI Listing |
Sovrem Tekhnologii Med
March 2025
DSc, Leading Researcher; ITMO University, 49, Bldg. A, Kronverksky Pr., Saint Petersburg, 197101, Russia.
Unlabelled: Application of fluorescent redox-sensitive nanoparticles in current biomedicine ensures high sensitivity and accuracy of biovisualization. Nanoparticles are potent as they can long circulate in the blood, where the level of glutathione is relatively low, and are destroyed in tumor cells, releasing loaded dyes or drugs. was to develop new nanoparticles based on trithiocyanuric acid for biovisualization of malignant tumors and study capabilities of the developed nanoparticles.
View Article and Find Full Text PDFJ Nanobiotechnology
March 2025
Department of Gastroenterology, National Clinical Research Center for Digestive Diseases, The First Affiliated Hospital of Naval Medical University/Changhai Hospital, Naval Medical University, Shanghai, 200433, China.
I therapy is clinically unfeasible for anaplastic thyroid carcinoma (ATC), due to lack of active targets and ATC's resistance to radiation. Novel radionuclide-labeled targeted nano-drug delivery systems have exhibited the potential of prominent tumor imaging and remedy. Capitalizing on recent research achievements in nanotechnology and nuclear medicine, we sought to develop a radiolabeled nano-drug, which could specifically accumulate in ATCs via tumor-selective targeted delivery system and which could treat the tumors with both targeted and radionuclide therapeutics.
View Article and Find Full Text PDFJ Hazard Mater
February 2025
School of Civil and Environmental Engineering, College of Engineering, Cornell University, 220 Hollister Hall, 527 College Ave, Ithaca, NY 14853, United States. Electronic address:
The efficacy of implementing granular activated carbon (GAC) treatment in combination with pre- or post-chlorination for mitigating disinfection byproducts (DBPs) in drinking water has been promising, yet its impact on water toxicity remains unclear, necessitating cost-effective and informative effect-based toxicity assessment. This study, using recently developed yeast toxicogenomic and human cell RT-qPCR assays targeting DNA and oxidative stress, compares the toxicity level and nature of water treated through a pilot-scale GAC system with post-chlorination (GAC/Cl) or pre-chlorination upstream of GAC (Cl/GAC/Cl), with water treated by chloramination (Cl/NHCl). Experiments were conducted at environmentally relevant bromide and iodide levels across three GAC beds.
View Article and Find Full Text PDFFront Nutr
February 2025
Department of Nutritional Behaviour, Max Rubner-Institut (MRI) - Federal Research Institute of Nutrition and Food, Karlsruhe, Germany.
Background: Nutrient intake during the phase of complementary feeding is pivotal for healthy development, yet current data for European infants are lacking.
Objective: To provide latest data on energy and nutrient intake of infants in Germany, to compare these with the Dietary Reference Values (DRVs) of the European Food Safety Authority, and to assess the contribution of vitamin D supplementation and commercial infant foods to nutrient intake.
Design: Analyses are based on weighed food records (3 + 1 day) of 118 infants aged 6-11 months from the representative cross-sectional Children's Nutrition Survey to Record Food Consumption (KiESEL) conducted in Germany from 2014 to 2017.
J Med Case Rep
March 2025
Interventional Pulmonology, Department of Medicine, University of California San Diego, La Jolla, CA, 92037, USA.
Background: Follicular variant papillary thyroid carcinoma is a distinct subtype of papillary thyroid carcinoma that can occasionally present with aggressive features, including distant metastases and extrathyroidal extension. While radioactive iodine ablation is a well-established treatment for residual disease, its post-treatment effects on tracheal and paratracheal structures remain poorly characterized.
Case Presentation: A 22-year-old male individual of Taiwanese descent presented with an enlarged neck mass and was diagnosed with follicular variant papillary thyroid carcinoma.
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