Successful recovery from extreme weather events is key to avoid long-term poverty implications. Yet, in disaster prone regions, there may not always be enough time to recover between events. There is a common narrative that the resulting incomplete recoveries aggravate adverse impacts, but approaches allowing for a systematic quantitative assessment are missing. Here, we extend an agent-based model to study welfare effects in the Philippines depending on household exposure and income. We find that incomplete recoveries increase cumulative consumption and well-being losses across the study period 2000-2018 by 40%. While low-income households suffer the highest well-being losses, the effect of incomplete recoveries is most relevant for middle-income households. Consequently, losses can be critically underestimated when drawing conclusions about the impacts of recurrent events based on the impacts of individual events. Accounting for incomplete recoveries may help to better prepare for an intensification of extreme events under climate change.
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http://dx.doi.org/10.1016/j.isci.2024.111733 | DOI Listing |
Int J Mol Sci
March 2025
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Kyung Hee University Medical Center, Kyung Hee University, Seoul 02447, Republic of Korea.
Facial nerve injury can lead to significant functional impairment, emotional impacts, and difficulties in social and economic activities. Although peripheral nerves have the potential for recovery, incomplete regeneration can pose challenges. Suppressor of Mothers Against Decapentaplegic Homolog (SMAD) proteins are crucial in the nerve-regeneration process.
View Article and Find Full Text PDFNeurology
April 2025
Brain Health and Wellness Research Program, St. Michael's Hospital, Unity Health Toronto, Ontario, Canada.
Background And Objectives: Medical clearance for return to play (RTP) after sports-related concussion is based on clinical assessment. It is unknown whether brain physiology has entirely returned to preinjury baseline at the time of clearance. In this longitudinal study, we assessed whether concussed individuals show functional and structural MRI brain changes relative to preinjury levels that persist beyond medical clearance.
View Article and Find Full Text PDFBr J Surg
March 2025
Department of Anaesthesia, University Medical Centre Utrecht, Utrecht, The Netherlands.
Background: The TRACE (Routine posTsuRgical Anaesthesia visit to improve patient outComE) RCT did not show any perioperative benefit from ward-based visits by anaesthetists after surgery. The aim of this study was to evaluate the impact of this intervention on longer-term outcomes.
Methods: Patients were followed up in the TRACE RCT to 1 year in nine hospitals in the Netherlands.
Medicine (Baltimore)
March 2025
Department of Rehabilitation Medicine, Nara Prefecture General Medical Center, Nara, Japan.
Objective: Patients with cerebrovascular disease tend to exhibit patterned hemiplegia, such as the Wernicke-Mann posture. Delayed cessation of synkinesis is a major factor impeding hemiplegic recovery; however, effective rehabilitation for acute synkinesis has not been established. This study aimed to evaluate the efficacy and feasibility of a novel treatment using a low-frequency therapeutic device for the cessation of synkinesis in patients with incomplete paralysis and cerebrovascular disease.
View Article and Find Full Text PDFPediatr Blood Cancer
March 2025
Ben Towne Center for Childhood Cancer Research, Seattle Children's Research Institute and Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, Washington, USA.
Background: Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and although many patients respond to induction therapy, those who relapse or have refractory disease face a poor prognosis. Venetoclax has promising preclinical and clinical activity in ALL. Here, we report the safety and preliminary efficacy of venetoclax combined with chemotherapy in pediatric and adolescent/young adult patients with relapsed/refractory ALL.
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