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W O Crystal and ICG Labeled Macrophage: An Efficient Targeting Vector for Fluorescence Imaging-guided Photothermal Therapy.
Biomed Environ Sci
January 2025
Department of Urology, The Third Medical Center, Chinese People's Liberation Army (PLA) General Hospital, Beijing 100853, China.
Bornite (CuFeS) nanocrystals as an ultrasmall biocompatible NIR-II contrast agent for photoacoustic imaging.
Photoacoustics
December 2024
Department of Biomedical Engineering, Tulane University, 6823 St. Charles Ave, New Orleans, LA 70118, United States.
In this study, we demonstrate the potential of the bornite crystal structure (CuFeS) of copper iron sulfide as a second near infrared (NIR-II) photoacoustic (PA) contrast agent. Bornite exhibits comparable dose-dependent biocompatibility to copper sulfide nanoparticles in a cell viability study with HepG2 cells, while exhibiting a 10-fold increase in PA amplitude. In comparison to other benchmark contrast agents at similar mass concentrations, bornite demonstrated a 10× increase in PA amplitude compared to indocyanine green (ICG) and a 5× increase compared to gold nanorods (AuNRs).
View Article and Find Full Text PDFCombining hybrid cell membrane modified magnetic nanoparticles and inverted microfluidic chip for in situ CTCs capture and inactivation.
Biosens Bioelectron
November 2024
State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, 2699 Qianjin Street, Changchun, 130012, China. Electronic address:
Circulating tumor cells (CTCs) serve as crucial indicators for tumor occurrence, progression, and prognosis monitoring. However, achieving high sensitivity and high purity capture of CTCs remains challenging. Additionally, in situ capture and synchronous clearance hold promise as methods to impede tumor metastasis, but further exploration is needed.
View Article and Find Full Text PDFMagnetic graphene oxide functionalized alginate-g-poly(2-hydroxypropylmethacrylamide) nanoplatform for near-infrared light/pH/magnetic field-sensitive drug release and chemo/phototherapy.
Int J Pharm
June 2024
Department of Chemistry, Faculty of Engineering and Natural Sciences, Kırıkkale University, Yahşihan, 71450 Kırıkkale, Turkey. Electronic address:
Multifunctional nanoplatforms developed from natural polymers and graphene oxide (GO) with enhanced biological/physicochemical features have recently attracted attention in the biomedical field. Herein, a new multifunctional near-infrared (NIR) light-, pH- and magnetic field-sensitive hybrid nanoplatform (mGO@AL-g-PHPM@ICG/EP) is developed by combining iron oxide decorated graphene oxide nanosheets (mGO) and poly(2-hydroxypropylmethacrylamide) grafted alginate (AL-g-PHPM) copolymer loaded with indocyanine green (ICG) and etoposide (EP) for chemo/phototherapy. The functional groups, specific crystal structure, size, morphology, and thermal stability of the nanoplatform were fully characterized by XRD, UV, FTIR, AFM/TEM/FE-SEM, VSM, DSC/TG, and BET analyses.
View Article and Find Full Text PDFDoes glaze firing affect the strength of advanced lithium disilicate after simulated defects?
Clin Oral Investig
November 2023
Department of Dental Materials Science, Academic Centre for Dentistry Amsterdam (ACTA), Universiteit Van Amsterdam and Vrije Universiteit, Gustav Mahlerlaan 3004, 1081 LA, Amsterdam, Noord-Holland, The Netherlands.
Objective: To study the influence of glazing on strength repair of lithium disilicate glass-ceramics after defect incorporation in different production processing phases.
Materials And Methods: Bar-shaped specimens (1 × 1 × 12 mm, n = 280; 20/group) made from different lithium disilicate ceramics (IPS e.max CAD, Ivoclar, "LD" or advanced lithium disilicate CEREC Tessera, Dentsply Sirona, "ALD") were exposed to 7 different protocols: crystallized without (c) and with glaze layer (cg), with a defect incorporated before crystallization without (ic) and with glaze layer (icg), with a defect after crystallization without (ci) or with glaze layer (cig), and defect incorporated after the glaze layer (cgi).
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