The emergence of antibiotic-resistant strains caused by the extensive use of antibiotics in the world requires a preventive approach to stop the infection spread, especially in a hospital setting. So, there is a growing demand for materials that can inhibit bacteria growth or have bactericidal effects. In this paper, an inexpensive and durable Cu-containing strontium-modified phosphate glass with a considerable antimicrobial effect is proposed. The basic physical properties of the material are studied, and its antimicrobial effect is evaluated on Staphylococcus aureus bacteria, known to be the most common problem in hospital environments because of healthcare-associated infections. The glass powders demonstrate strong antibacterial efficacy with a concentration of only a few mg/mL, sufficient to eradicate the entire bacterial colonies within 24 h. Bulk surfaces of these glasses inhibit bacterial growth and release low, non-toxic levels of their constituent elements into simulated body fluid. On the basis of the obtained results, it is shown that the proposed glass can be used as a structural material for various medical equipment and/or components of antimicrobial coating/paint not only in medicine but also for high touch point articles in public places like schools, gyms, public offices and similar.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11806054 | PMC |
http://dx.doi.org/10.1038/s41598-025-88781-z | DOI Listing |
Cancer Rep (Hoboken)
March 2025
Department of Surgery, Urology, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Background: Prostate cancer (PCa) is a significant contributor to male mortality globally, including in the Democratic Republic of the Congo (DRC). Various factors play a role in its onset and progression. The impact of trace elements and other risk factors on the survival of PCa patients is not extensively studied in this setting.
View Article and Find Full Text PDFAntioxidants (Basel)
February 2025
School of Human Nutrition, McGill University, MacDonald Campus, Sainte-Anne-de-Bellevue, QC H9X 3V9, Canada.
Background: Associations of antioxidants in prenatal over-the-counter multivitamin-mineral (OTC MVM) supplements with in-utero oxidative stress (OS), antioxidant capacity, and fetal growth are limited. Our objectives were to determine if five fetal ultrasound measurements [biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), femur length (FL), and estimated fetal weight] were associated with OTC MVM supplements and with minerals, biomarkers of OS, and total antioxidant capacity in amniotic fluid (AF).
Methods: For this retrospective study, 176 pregnant women who had undergone age-related amniocentesis for genetic testing were included.
Chemosphere
February 2025
National Institute of Health Dr. Ricardo Jorge, Avenida Padre Cruz, 1649-016, Lisboa, Portugal.
The application of animal manure to agricultural soil is a very common practice to improve soils fertility, providing a rich source of organic matter and nutrients. However, the presence of certain trace elements in the manure can result in a threat for food safety and the environment. In addition to their potential toxic effects on crops, animal and humans, certain metals such as cadmium, chromium, copper, nickel, mercury, cobalt, lead and zinc may play a role in the emergence and spread of antibiotic resistance, as they can increase the selective pressure on bacteria.
View Article and Find Full Text PDFSmall
February 2025
School of Chemical, Materials and Biomedical Engineering, College of Engineering, University of Georgia, Athens, GA, 30602, USA.
Nitric oxide (NO) is a potent gasotransmitter that exhibits a pleiotropic effect in regulating homeostasis and pathophysiology. Though it is a versatile biomaterial, silicone-based devices are still challenged by implant-associated infections and fibrous capsule formation complications. Here, a NO-generating (NOgen) interface is developed from copper or strontium-doped mesoporous bioactive glass-based coating on silicone substrates to facilitate metal-ion catalysis of endogenous S-nitrosothiols.
View Article and Find Full Text PDFEnviron Pollut
March 2025
Research Division, Montana Bureau of Mines and Geology, Butte, MT, United States.
Across the United States, rural residents rely on unregulated and generally unmonitored private wells for drinking water, which may pose serious health risks due to unrecognized contaminants. We assessed the nature, degree, and spatial distribution of cumulative health risks from inorganic contaminants in groundwater. Our analysis included nearly 84,000 data points from 6500+ wells, across 51 of Montana's 98 watersheds, using a public groundwater database.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!