Purpose: The aim of the study is to determine the effect of the macronutrient content of breast milk on the anthropometric measurements of infants in the first 6 months.
Background: Breast milk contains essential macro- and micronutrients needed in the early stages of an infant's development. Current literature highlights the importance of understanding how breast milk's macronutrient content influences infant growth.
Methods: The study protocol has been published in PROSPERO (CRD42023425550). This study adheres to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) guideline. Studies published between January 1, 2016, and June 2, 2023, were reviewed across 6 databases. The Joanna Briggs Institute Cohort Studies checklist was used to assess methodological quality. Effect sizes were calculated using both fixed-effects and random-effects models.
Results: Six studies were included in the systematic review and meta-analysis. The meta-analysis indicated a significant relationship between lactose content in breast milk and infant weight gain, length growth, and head circumference, as well as between fat-lipid content and infant weight gain within the first 6 months (P < .05). No significant relationship was found between protein or carbohydrate content of milk and anthropometric measurements of infants in the first 6 months (P > .05).
Conclusion And Implications: The findings suggest that macronutrient concentrations in breast milk are important determinants of infant growth. Further research with high level of evidence and standard methodological protocols is recommended to elucidate the relationships between breast milk content and infant growth.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/JPN.0000000000000903 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Dynamic changes in the gut microbiota of SPF Bama piglets during breast and formula feeding.
Front Microbiol
February 2025
Key Laboratory of Livestock and Poultry Multi-omics, Ministry of Agriculture and Rural Affairs, Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, China.
The gut microbiota plays a crucial role in the growth performance, health status, and welfare of pigs. Breast milk is a key factor in the colonization of gut microbiota and the overall health of newborn piglets. With advancements in breeding technology, formula milk has been widely adopted as a substitute for breast milk.
View Article and Find Full Text PDFBaby-Led Weaning vs. Traditional Complementary Feeding-Differences in Feeding Practices Among Polish Children Aged 6-36 Months-A Cross-Sectional Study.
Nutrients
March 2025
Department of Human Nutrition, Department of Dietetics, School of Public Health in Bytom, Medical University of Silesia in Katowice, ul. Jordana 19, 41-808 Zabrze, Poland.
Unlabelled: Complementary feeding involves introducing additional foods to a child's diet, influenced by the child's age, developmental stage, and skills, such as sucking, swallowing, and chewing. The WHO and ESPGHAN recommend exclusive breastfeeding for the first six months, with the gradual introduction of complementary foods thereafter. The baby-led weaning (BLW) method emphasises self-feeding and the early introduction of solid foods, fostering independence and development.
View Article and Find Full Text PDFThe Human Milk Oligosaccharide Lacto-N-Fucopentaose III Conjugated to Dextran Inhibits HIV Replication in Primary Human Macrophages.
Nutrients
March 2025
Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
: Individuals with HIV on combined antiretroviral therapy (ART) with virologic suppression exhibit chronic immune activation and immune dysfunction. Numerous studies have shown that human milk oligosaccharide (HMO) controls the postnatal transmission of HIV-1, but its effect on adult HIV-1 infection is not known. The purpose of this study was to investigate the anti-HIV activity of Lacto-N-fucopentaose III (LNFPIII) in adult blood-borne macrophages.
View Article and Find Full Text PDFThe "Jekyll Side" of the S100B Protein: Its Trophic Action in the Diet.
Nutrients
February 2025
Department of Movement, Human, and Health Sciences, University of Rome "Foro Italico", 00135 Rome, Italy.
The calcium-binding S100B protein is concentrated in glial cells (including enteroglial cells) in the nervous system. Its conformation and amino acid composition are significantly conserved in different species; this characteristic suggests conserved biological role(s) for the protein. The biological activity is concentration-dependent: low physiological concentrations exert a neurotrophic effect, while high concentrations exert a proinflammatory/toxic role.
View Article and Find Full Text PDFZinc Concentration in Breast Milk Is Inversely Correlated with the Zinc Supplementation Requirements of Preterm Infants.
Nutrients
February 2025
Department of Pediatrics, Showa University School of Medicine, 1-5-8, Hatanodai, Shinagawa-ku, Tokyo 142-8666, Japan.
Zinc is an essential trace element that is crucial for numerous biological processes, including protein synthesis, antioxidant activity, and bone calcification. Preterm infants are at high risk of zinc deficiency owing to inadequate zinc stores at birth and the rapid decline in zinc concentration in breast milk. This study aimed to evaluate the relationship between zinc concentrations in breast milk and zinc supplementation in preterm infants.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!