A 39-year-old woman presented with left neck masses for 4 months and epiphora of the left eye for 3 weeks. Ultrasonography revealed a mass in the left parotid gland and multiple cervical lymph nodes. Biopsy of the mass in the left parotid gland revealed infiltrating ductal carcinoma. F-fluorodeoxyglucose positron emission tomography/computed tomography scan was undertaken, which showed a mass in the left parotid gland and multiple cervical lymph nodes with high metabolism. A nodule in the left nasolacrimal duct with high metabolism was observed. The nodule was surgically removed and pathologically confirmed as metastatic parotid ductal carcinoma.
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http://dx.doi.org/10.4274/mirt.galenos.2024.46667 | DOI Listing |
J Surg Case Rep
March 2025
Department of Thoracic Surgery and Breast Surgery, Asahikawa Medical University Hospital, 078-8510, 2-1-1-1 Midorigaoka Higashi, Asahikawa, Hokkaido 078-8510, Japan.
Occult breast cancer (OBC) is a rare form of breast cancer that is detected due to regional lymph node metastasis in the axilla. The patient was a 77-year-old woman. Twenty-four years previously, she had undergone a breast-conserving surgery and axillary lymph node dissection for left breast cancer.
View Article and Find Full Text PDFJ Surg Case Rep
March 2025
Department of Pathology, Henry Ford Health, 2799 W Grand Blvd., Detroit, MI 48202, United States.
We report a young female patient diagnosed with an invasive ductal carcinoma at the site of a prior cosmetic nipple piercing. She had no significant familial, genetic, or other carcinogenic risk factors to account for her presentation. A review of the literature confirms that trauma can occasionally be associated with invasive breast cancer, but such a connection has not previously been related to nipple piercing procedures.
View Article and Find Full Text PDFJ Genet Eng Biotechnol
March 2025
State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, China; Department of Hepatobiliary and Echinococcosis Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China. Electronic address:
Background: Few studies revealed that stromal genes regulate the tumor microenvironment (TME). However, identification of key-risk genes in the invasive ductal breast carcinoma-associated stroma (IDBCS) and their associations with the prediction of risk group remains lacking.
Methods: This study used the GSE9014, GSE10797, GSE8977, GSE33692, and TGGA BRCA datasets.
Gan To Kagaku Ryoho
February 2025
Dept. of Surgery, Kansai Rosai Hospital.
A 50-year-old female presented with abdominal pain. Upper gastrointestinal endoscopy revealed a 30 mm ulcerative lesion extending from the duodenal bulb to the descending portion, and biopsy confirmed poorly differentiated adenocarcinoma. Abdominal contrast-enhanced CT scan showed an hypovascular tumor in the pancreatic head with suspected invasion into the duodenum, along with enlarged #8 lymph node.
View Article and Find Full Text PDFCells
February 2025
Department of Gastroenterology and Internal Medicine, Medical University of Bialystok, 15-276 Bialystok, Poland.
An association between gut microbiota and the development of pancreatic ductal adenocarcinoma (PDAC) has been previously described. To better understand the bacterial microbiota changes accompanying PDAC promotion and progression stimulated by inflammation and fecal microbiota transplantation (FMT), we investigated stool and pancreatic microbiota by 16s RNA-based metagenomic analysis in mice with inducible acinar transgenic expressions of KrasG12D, and age- and sex-matched control mice that were exposed to inflammatory stimuli and fecal microbiota obtained from mice with PDAC. Time- and inflammatory-dependent stool and pancreatic bacterial composition alterations and stool alpha microbiota diversity reduction were observed only in mice with a Kras mutation that developed advanced pancreatic changes.
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