AI Article Synopsis
- The study used 2-D PAGE to analyze polypeptide patterns in nine neuroblastoma cell lines and thirteen other types of cell lines.
- Of the 600 polypeptide spots examined, one was unique to neuroblastoma, while three showed significantly higher levels and one showed lower levels in neuroblastoma compared to other cell lines.
- These findings help establish a foundation for deeper investigation into the polypeptide patterns specific to neuroblastoma cells.
Article Abstract
Polypeptide patterns of nine neuroblastoma and thirteen other cell lines were analyzed by 2-D PAGE. Of 600 polypeptide spots scored one was present in all neuroblastoma cell lines and none of the other cell types analyzed. Three were markedly increased in intensity in neuroblastoma relative to other cell lines, and one was markedly decreased in neuroblastoma and melanoma. These data provide a basis for a more detailed analysis of the polypeptide pattern of neuroblastoma cells.
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