Background: Alcohol drinking can cause hyperuricemia (HUA), but few studies have explored alcohol abstinence's health effects, particularly the abstinence duration on HUA. This study aimed to evaluate the associations of abstinence with HUA in rural Chinese adults.
Methods: This was a cross-sectional study of 38,855 participants (15,371 males and 23,484 females) using the baseline data (2015-2017) from the Henan Rural Cohort Study. A questionnaire survey collected information on alcohol consumption patterns. Multivariate logistic regression analyses were used to evaluate the associations of type of alcoholic beverages, abstinence status and abstinence duration with HUA, respectively. Restricted cubic spline models were applied to visualize the dose-response trend of HUA risk with increasing abstinence duration.
Results: 3,978 cases of 38,855 participants were identified with HUA. Total alcohol intake, including beer, liquor and rice wine intake was significantly associated with the increased risk of HUA, especially for male participants. Compared with current drinkers, former drinkers and non-drinkers presented lower ORs (95%CIs) of 0.686 (0.676, 0.844) and 0.718 (0.649, 0.793) for HUA. Furthermore, the aORs (95%CIs) for those former drinkers with < 5, 6-10 and ≥ 11 years abstinence duration were 0.868 (0.693, 1.086), 0.753 (0.519, 1.092) and 0.717 (0.517, 0.990), respectively. In addition, the risk of HUA decreased with the increasing years of abstinence duration (P for trend < 0.050) and negative linear dose-response associations were observed.
Conclusion: Former drinkers were associated with a reduced risk of HUA compared with current drinkers. Moreover, sustained alcohol abstinence could be beneficial for preventing HUA.
Clinical Trial Registration: The Henan Rural Cohort Study was registered on the Chinese Clinical Trial Register (Registration number: ChiCTR-OOC-15006699). Date of registration: 2015-07-06 http://www.chictr.org.cn/showproj.aspx?proj=11375 .
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11800491 | PMC |
| http://dx.doi.org/10.1186/s12889-025-21545-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Study on the pharmacodynamic substances and mechanism of hepatoprotection of Acanthus ilicifolius Linn.
Phytomedicine
March 2025
Key Laboratory of Novel Food Resources Processing, Ministry of Agriculture and Rural Affairs/Key Laboratory of Agro-Products Processing Technology of Shandong Province, Institute of Agro-Food Science and Technology, Shandong Academy of Agricultural Sciences, 23788 Gongye North Road, Jinan 250100, PR China. Electronic address:
Background: The coastal wetland mangrove plant Acanthus ilicifolius l. (AI) is used as traditional medicine for liver protection and liver fibrosis treatment, but the pharmacodynamics of the hepatoprotective substance and the mechanisms of liver protection are not clear.
Purpose: This work aimed to assess the liver-protective ability of AI and elucidate the pharmacodynamics of the hepatoprotective substance of AI responsible for its liver activity.
Impact of postharvest ripening on peach quality: Aroma release and formation mechanism.
Food Chem
March 2025
Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences (CAAS)/ Key Laboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, 100193 Beijing, China. Electronic address:
Peach aroma could be further released during postharvest ripening but the mechanism of aroma formation was still unclear. During peaches stored at 4 °C for 0-8 days (D0-8), flavoromics were performed to reveal aroma release and their formation pathways. γ-Decalactone content in D2 and D4 increased by 83 % and 60 % through oleic acid metabolism compared with D0, strengthening peach-like aroma.
View Article and Find Full Text PDFLongitudinal reconfiguration of multifaceted fish α and β diversity triggered by non-native species invasion in tropic rivers of Hainan Island.
J Environ Manage
March 2025
Pearl River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Key Laboratory of Prevention and Control for Aquatic Invasive Alien Species, Ministry of Agriculture and Rural Affairs, Guangzhou, 510380, China; Key Laboratory of Alien Species and Ecological Security (CAFS), Pearl River Fisheries Research Institute, Chinese Academy of Fisheries Science, Guangzhou, 510380, China. Electronic address:
Human-mediated fish invasions have reconfigured the native fish faunas throughout the freshwater ecosystems worldwide. Beyond the well-documented homogenization reported in temperate basins, our knowledge on how multifaceted biodiversity response to fish invasions in tropic rivers remains poorly understood. It is also hanged in doubt that how fish invasions modify the longitudinal patterns of fish faunas under the concept of river continuum.
View Article and Find Full Text PDFBiodetoxification of both AFB1 and ZEN by Bacillus subtilis ZJ-2019-1 in gastrointestinal environment and in mice.
Mycotoxin Res
March 2025
Institute of Feed Research, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.
Aflatoxin B1 (AFB1) and zearalenone (ZEN) are the most prevalent mycotoxins in production, posing a serious threat to human and animal health. Therefore, it is very urgent to find a safe and efficient method for the biodegradation of these mycotoxins. Our previous study demonstrated that Bacillus subtilis ZJ-2019-1 moderately degrades both mycotoxins in vitro and ZEN in female gilts.
View Article and Find Full Text PDFStarvation tolerance and effects on fitness of predatory mite Amblyseius orientalis.
Exp Appl Acarol
March 2025
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Amblyseius orientalis Ehara (Mesostigmata: Phytoseiidae) has garnered significant attention as an effective predatory mite for controlling spider mites in fruit production in China. However, despite its considerable potential for pest management, A. orientalis may face food shortages during transportation and field application.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!