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Transfusion of modified whole blood versus blood components therapy in patients with severe trauma: Randomized controlled trial protocol (WEBSTER trial).
Injury
January 2025
División de Cirugía de Trauma y Emergencias, Departamento de Cirugía, Fundación Valle del Lili, Cali, Colombia; Departamento de Cuidado Intensivo, Fundación Valle del Lili, Cali, Colombia; Departamento de Cirugía, Universidad del Valle, Cali, Colombia.
Hemostatic resuscitation is a mainstay in the management of trauma patients. Factors such as blood loss and tissue injury contribute to coagulation and hemodynamic status imbalances. Hemorrhage remains a leading cause of death in trauma patients, despite advances in strategies such as damage control surgery, massive transfusion protocol, and intensive care.
View Article and Find Full Text PDFCongenital heart disease-related mortality during the first year of life: The peruvian experience.
Int J Cardiol Congenit Heart Dis
March 2025
Department of Cardiovascular Medicine, Mayo Clinic, Jacksonville, FL, USA.
Introduction: Congenital heart disease (CHD) affects 1 % of all live births globally, with critical CHD (CCHD) requiring early intervention to avoid neonatal mortality. To date, CHD-related mortality within the first year of life and its associated factors have not been studied in Peru.
Methods: This is an observational secondary analysis using the Peruvian National Computerized System of Deaths, data from 2017 to 2021.
Reduction of surgical site infection rates in elective colorectal surgery by means of a nationwide interventional surveillance programme. A cohort study.
Enferm Infecc Microbiol Clin (Engl Ed)
March 2025
VINCat Programme Surveillance of Healthcare Related Infections in Catalonia, Departament de Salut, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC, CB21/13/00009), Instituto Carlos III, Madrid, Spain; Department of Infectious Diseases, Hospital Universitari de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Spain.
Introduction: Colorectal surgery has the highest surgical site infection (SSI) rates of all abdominal surgeries. Epidemiological surveillance is an excellent instrument to reduce SSI rates, but its effects may be time-limited and need to be monitored periodically. This study analyses the effectiveness of an interventional surveillance programme with regard to reducing SSI rates after elective colorectal surgery.
View Article and Find Full Text PDFEl índice triglicéridos-glucosa como predictor de eventos cardiovasculares en pacientes con psoriasis y tratamiento sistémico: un estudio observacional de 150 pacientes.
Actas Dermosifiliogr
March 2025
Unidad de Salud Pública y Atención Ambiental, Departamento de Medicina Preventiva y Salud Pública, Ciencias de los Alimentos, Toxicología y Medicina Forense, Universidad de Valencia, España.CIBER en Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, España.
Psoriasis is consistently associated with an elevated cardiovascular risk. However, biochemical parameters are needed to predict cardiovascular events in these patients. Therefore, we conducted a retrospective cohort study with psoriatic patients undergoing systemic treatment to analyze the value of the triglyceride-glucose (TyG) index in predicting the development of major adverse cardiovascular events (MACE).
View Article and Find Full Text PDFFontan-Associated Liver Disease (FALD) in the EUROFontan Experience. An Insight into European Awareness.
Pediatr Cardiol
March 2025
Pediatric and Congenital Cardiac Surgery, Department of Precision and Regenerative Medicine and Jonian Area, University of Bari Aldo Moro, Bari, Italy.
Fontan-Associated Liver Disease (FALD) is a dramatically emerging problem even if not precisely defined in term of debated diagnosis and surveillance protocols. We analyze FALD prevalence, clinical impact and implications in a European cohort of patients. It's a retrospective observational multicenter study including Fontan patients operated between 1990 and 2022.
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