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Insect metamorphosis and chitin metabolism under miRNA regulation: a review with current advances.
Pest Manag Sci
March 2025
Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang, China.
Insect metamorphosis is a complex developmental process regulated by microRNAs (miRNAs) and hormonal signaling pathways. Key genes driving insect ontogenic changes are precisely modulated by miRNAs, which interact with 20-hydroxyecdysone (20E) and juvenile hormone (JH) to coordinate developmental transitions. Over the past decade, significant progress has been made in understanding miRNA biogenesis, their regulatory roles in gene expression, and their involvement in critical biological processes, including metamorphosis and chitin metabolism.
View Article and Find Full Text PDFInorganic Nanomaterials Meet the Immune System: An Intricate Balance.
Adv Healthc Mater
March 2025
Department of Pharmacy, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Cembrano 4, Genoa, 16148, Italy.
The immune system provides defense against foreign agents that are considered harmful for the organism. Inorganic nanomaterials can be recognized by the immune system as antigens, inducing an immune reaction dependent on the patient's immunological anamnesis and from several factors including size, shape, and the chemical nature of the nanoparticles. Furthermore, nanomaterials-driven immunomodulation might be exploited for therapeutic purposes, opening new horizons in oncology and beyond.
View Article and Find Full Text PDFAdvances in Polymer-Based Self-Adjuvanted Nanovaccines.
Small
March 2025
Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Centre for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu, 610041, P. R. China.
Nanovaccines, as a new generation of vaccines, have garnered significant interest due to their exceptional potential in enhancing disease prevention and treatment. Their unique features, such as high stability, antigens protection, prolonged retention, and targeted delivery to lymph nodes, immune cells, and tumors, set them apart as promising candidates in the field of immunotherapy. Polymers, with their superior degradability, capacity to mimic pathogen characteristics, and surface functionality that facilitates modifications, serve as ideal carriers for vaccine components.
View Article and Find Full Text PDFA comparative analysis of influenza and COVID-19: Environmental-ecological impacts, socioeconomic implications, and future challenges.
Biosaf Health
December 2024
Vanke School of Public Health, Tsinghua University, Beijing 100084, China.
In the last century, global pandemics have been primarily driven by respiratory infections, which consistently rank among the top 20 causes of death worldwide. The coronavirus disease 2019 (COVID-19) pandemic has underscored the intricate nature of managing multiple health crises simultaneously. In recent years, climate change has emerged as a major biosafety and population health challenge.
View Article and Find Full Text PDFRecent advancements in wearable sensors: integration with machine learning for human-machine interaction.
RSC Adv
March 2025
School of Humanities and Management, Heilongjiang University of Chinese Medicine Harbin PR China.
Wearable sensors have emerged as a transformative technology, enabling real-time monitoring and advanced functionality in various fields, including healthcare, human-machine interaction, and environmental sensing. This review provides a comprehensive overview of the latest advancements in wearable sensor technologies, focusing on innovations in sensor design, material flexibility, and integration with machine learning. We explore the feasibility of wearable electronics in achieving high-performance, flexible devices and discuss their potential to enhance human-machine interactions through intelligent data processing and decision-making.
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