Severity: Warning
Message: fopen(/var/lib/php/sessions/ci_sessionr4tm3nti4t1u1s8drntbab5ck6k77khd): Failed to open stream: No space left on device
Filename: drivers/Session_files_driver.php
Line Number: 177
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
Severity: Warning
Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)
Filename: Session/Session.php
Line Number: 137
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
The last decade has seen the introduction of two new licensed therapies for thrombotic thrombocytopenic purpura (TTP)-caplacizumab and recombinant ADAMTS 13 (rADAMTS 13), for immune (iTTP) and congenital TTP (cTTP) respectively. They improve acute TTP outcomes, reduce the need for plasma therapy, time to clinical response and treatment burden. Future pathways need to replace plasma exchange in acute TTP and optimise/personalise rADAMTS 13 in cTTP. Future emphasis should focus on additional monoclonals/treatments to tackle ADAMTS 13 antibodies.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1182/blood.2024026390 | DOI Listing |
Nurs Adm Q
March 2025
Author Affiliations: Arizona Hospital and Healthcare Association (Ms Buchda and Dr Ofafa); and OpusVi, Toronto, Canada (Drs Cato and DeLoia).
The post-pandemic healthcare landscape significantly impacted the professional nursing workforce by exacerbating existing challenges, including the academic-practice gap of new nurse graduates. Transition to practice (TTP) programs have been proven effective in supporting newly licensed registered nurses as they move into practice. A well-designed TTP program empowers new nurses to become resilient and competent, enhancing patient care and contributing to a healthier work environment.
View Article and Find Full Text PDFCureus
February 2025
Medicine, Queen Elizabeth Hospital, Hong Kong, HKG.
Thrombotic microangiopathy (TMA) represents a diverse group of conditions characterized by the presence of microangiopathic hemolytic anemia (MAHA), thrombocytopenia, and ischemic end-organ injury. Thrombotic thrombocytopenic purpura (TTP) is an important cause of TMA requiring urgent identification and therapeutic plasma exchange (TPE). Cancer-related TMA is commonly misdiagnosed as TTP.
View Article and Find Full Text PDFBiomed Eng Online
March 2025
Department of Neurosurgery, Affiliated Hospital 3201, Xi'an Jiaotong University, No. 783, Tianhan Avenue, Hanzhong, 723000, Shaanxi, China.
Objective: To investigate the predictive value of computer tomography (CT) imaging features for the risk of hemorrhagic transformation (HT) after mechanical thrombectomy for acute ischemic stroke with large vessel obstruction (AIS-LVO).
Methods: A total of 135 patients with AIS-LVO diagnosed and treated in our hospital from August 2021 to May 2023 were selected as the research subjects. Their clinical data were retrospectively analyzed.
J Neurointerv Surg
March 2025
Department of Neurosurgery, St Michael's Hospital, Toronto, Ontario, Canada.
Background: New generation flow-diverting stents have benefited from recent technological advances to reduce their thrombogenicity. This in vitro study is the first of its kind to compare multiple surface modified flow diverters with their bare metal counterparts.
Methods: A thrombin generation assay (TGA) was used to compare thrombin generation resulting from different stent types with glass beads (positive control) and plasma (negative control).
Cureus
February 2025
Nephrology, State University of New York Downstate Health Sciences University, Brooklyn, USA.
We present an unusual case of complement-mediated thrombotic microangiopathy (formerly known as atypical hemolytic uremic syndrome) associated with inflammatory disease in a young patient. A 26-year-old male patient with no significant past medical history presented to our emergency department with a four-week history of diffuse, moderate, cramping, non-radiating abdominal pain with no known aggravating or relieving factors. Abdominal pain was associated with nausea, vomiting, and bloody stools.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!