Objective This study aims to identify, determine, and assess the factors influencing nursing leadership and evaluate the effectiveness of interventions to enhance leadership among nurse practitioners (NPs). Methods This study employed an exploratory, descriptive qualitative design to examine nurse leaders' perceptions of nurse practitioner (NP) role expansion in India. Sixty senior nurse administrators were purposively sampled from healthcare and educational institutions in Telangana. Data collection, conducted between May and October 2024, utilized a structured questionnaire divided into quantitative and qualitative sections. Key themes identified through manual thematic analysis included the influence of nursing leadership, perceived benefits of NP roles, barriers to role expansion, and strategies to overcome challenges. Quantitative data, including demographic variables, were analyzed using SPSS software with descriptive statistics, chi-square tests, and ANOVA tests. A pilot study in Karnataka refined the questionnaire, ensuring its clarity and validity. Ethical approval was obtained, and participant confidentiality was maintained, enabling a robust exploration of leadership perspectives on NP role expansion. Results Approximately 66.7% of respondents perceived nursing leadership as pivotal in advocating for the NP role. Significant differences were observed in perceived benefits scores between males (3.8 ± 0.6) and females (4.2 ± 0.5). Similarly, significant differences were found in support for role expansion scores between males (3.7 ± 0.7) and females (3.8 ± 0.6). These findings indicate that females perceived greater benefits and support for NP role expansion compared to males. Furthermore, educational background and current positions were significantly associated with perceptions of challenges and support for NP role expansion. Conclusions The shortage of primary care physicians has highlighted the need to implement NP-led care in the country. The Indian Nursing Council (INC) has introduced an NP program in critical care nursing. Evidence demonstrates that NPs can effectively deliver a wide range of services, including assessment, diagnosis, treatment of minor ailments, curative and rehabilitative care, and referral services, particularly in underserved and deprived communities.
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http://dx.doi.org/10.7759/cureus.77009 | DOI Listing |
Cell Rep
March 2025
Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark. Electronic address:
Plasmacytoid dendritic cells (pDCs) play a pivotal role in immune responses, particularly against viral infections. pDCs exhibit diverse functions, including interferon production, cytokine secretion, and antigen presentation. Here, we investigate the antigen cross-presentation capacity of pDCs and their role in CD8 T cell activation.
View Article and Find Full Text PDFJ Clin Microbiol
March 2025
Laboratory of Medical Microbiology, Vaccine and Infectious Disease Institute, University of Antwerp, Antwerp, Belgium.
serotype 23B, a non-vaccine serotype, has shown an increasing prevalence and penicillin non-susceptibility among carriage and invasive pneumococcal disease (IPD) isolates. Recently, a novel penicillin non-susceptible genotype has emerged, named 23B1. In the framework of the Belgian pneumococcal carriage study, we studied the prevalence of 23B/23B1 among 586 23B strains (2016-2022) in 172 day care centers from 6- to 30-month-old children and among 130 pediatric 23B IPD isolates (2007-2021).
View Article and Find Full Text PDFEur J Immunol
March 2025
Department of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, People's Republic of China.
Toll-like receptors (TLRs) play a crucial role in the immune response to pathogen invasion. The TLR response patterns in teleost are significantly different from those in mammals. In this study, we systematically identified and characterized the TLR family of crucian carp (Carassius auratus).
View Article and Find Full Text PDFSovrem Tekhnologii Med
March 2025
MD, PhD, Head of the Laboratory of Solid Tumor Immunotherapy; Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency of Russia, 1, Bldg. 10, Ostrovityanova St., Moscow, 117513, Russia; Senior Researcher, Laboratory of Cell Technologies; Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies of the Federal Medical Biological Agency of Russia, 28 Orekhovy Blvd., Moscow, 115682, Russia; Senior Researcher, Laboratory of Molecular Regeneration Mechanisms; Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences, 32 Vavilov St., Moscow, 119991, Russia.
Unlabelled: Glioblastoma is the most aggressive primary brain tumor with poor prognosis characterized by resistance to standard treatments and immune evasion. Regulatory T lymphocytes (Tregs) play a key role in immune suppression in the tumor microenvironment and can be used as targets for malignant gliomas therapy. is to study migration of Tregs to the tumor site in the process of dynamic glioblastoma growth on the transgenic C57Bl/6-FoxP3-eGFP mouse line.
View Article and Find Full Text PDFJ Hosp Palliat Care
March 2025
Department of Social Welfare, Soongsil University, Seoul, Korea.
In 2018, the South Korean government launched a community care policy aimed at providing more extensive social services for older adults, the disabled, and mental health patients. This policy also included an expansion of home-based hospice services in response to the growing demand for hospice and palliative care. Despite these initiatives, social workers play a limited role in home-based hospice care, and those specializing in hospice and palliative care are not yet fully equipped to provide effective community care services.
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