National, subnational, and supranational entities are creating biodiversity strategy and action plans (BSAPs) to develop concrete commitments and actions to curb biodiversity loss, meet international obligations, and achieve a society in harmony with nature. In light of policymakers' increasing recognition of genetic diversity in species and ecosystem adaptation and resilience, this article provides an overview of how BSAPs can incorporate species' genetic diversity. We focus on three areas: setting targets; committing to actions, policies, and programs; and monitoring and reporting. Drawing from 21 recent BSAPs, we provide examples of policies, knowledge, projects, capacity building, and more. We aim to enable and inspire specific and ambitious BSAPs and have put forward 10 key suggestions mapped to the policy cycle. Together, scientists and policymakers can translate high level commitments, such as the Convention on Biological Diversity's Kunming-Montreal Global Biodiversity Framework, into concrete nationally relevant targets, actions and policies, and monitoring and reporting mechanisms.
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http://dx.doi.org/10.1093/biosci/biae106 | DOI Listing |
Adv Sci (Weinh)
March 2025
National Key Facility for Crop Gene Resources and Genetic Improvement/Key laboratory Grain Crop Genetic Resources Evaluation and Utilization Ministry of Agriculture and Rural Affairs, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, P. R. China.
Tartary buckwheat (Fagopyrum tataricum) is esteemed as a medicinal crop due to its high nutritional and health value. However, the genetic basis for the variations in Tartary buckwheat grain ionome remains inadequately understood. Through genome-wide association studies (GWAS) on grain ionome, 52 genetic loci are identified associated with 10 elements undergoing selection.
View Article and Find Full Text PDFFASEB J
March 2025
Department of Oncology, The Central Hospital of Yongzhou, Yongzhou, Hunan, China.
The ribophorin family, including RPN1, has been associated with tumor progression, but its specific role in pan-cancer dynamics remains unclear. Using data from TCGA, GTEx, and Ualcan databases, we investigated the relationship of RPN1 with prognosis, genomic alterations, and epigenetic modifications across various cancers. Differential analysis revealed elevated RPN1 expression in multiple cancer types, indicating a potential prognostic value.
View Article and Find Full Text PDFPhysiol Plant
March 2025
Plant Biodynamics Laboratory and Department of Plant Developmental Genetics, Institute of Biology Leiden, Leiden University, Leiden, The Netherlands.
The plant hormone auxin (Indole-3-Acetic Acid, IAA) is a key player in nearly every aspect of plant growth and development ranging from cell division and cell elongation to embryogenesis and root formation. The IAA level in specific tissues and cells is regulated by synthesis, conjugation, degradation and transport. Especially long-range polar auxin transport (PAT) has been the subject of numerous studies.
View Article and Find Full Text PDFNucleus
December 2025
School of Molecular Biosciences, Biotechnology Life Sciences, Washington State University, Pullman, WA, USA.
Replication timing during S-phase impacts mutation rates in yeast and human cancers; however, the exact mechanism involved remains unclear. Here, we analyze the impact of replication timing on UV mutagenesis in . Our analysis indicates that UV mutations are enriched in early-replicating regions of the genome in wild-type cells, but in cells deficient in global genomic-nucleotide excision repair (GG-NER), mutations are enriched in late-replicating regions.
View Article and Find Full Text PDFJ Cell Mol Med
March 2025
Department of Cardiology, The Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Recent research has revealed a close association between obesity and various metabolic disorders, including renal metabolic diseases, but the mechanism is still unknown. This study explored the role of p16INK4a in obesity-related kidney fibrosis and evaluated its potential as a therapeutic target. Using wild-type (WT) mice and p16 KO mice, we fed both groups a high-fat diet (HFD) for 6 months.
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