Background: ChatGPT, a chatbot launched by OpenAI in November 2022, has generated both excitement and concern within the healthcare education, research, and practice communities. This study aimed to explore the knowledge, perceptions, attitudes, and practices of undergraduate medical students regarding the use of ChatGPT and similar chatbots in their academic work.

Methods: An anonymous, structured questionnaire was developed using Google Forms and administered to medical students as part of a cross-sectional study. The survey targeted undergraduate medical students from four governorates in Egypt. The questionnaire link was distributed through social media platforms, including Facebook and WhatsApp. The survey comprised four sections: socio-demographic characteristics, perceptions, attitudes, and practices.

Results: The survey achieved a response rate of 96%, with 614 out of 640 approached students participating. Prior to the study, most respondents (78.5%) had personal experience using it. Overall, respondents demonstrated positive perceptions, attitudes, and practices toward ChatGPT, with mean scores exceeding 3 for all three variables: 3.99 ± 0.60 for perceptions, 3.01 ± 0.46 for attitudes, and 3.55 ± 0.55 for practices. In general, the students exhibited a high degree of trust in the model, with approximately half trusting the accuracy and reliability of the information provided by ChatGPT. However, more than two-thirds expressed apprehension about its potential misuse in medical education, and around 60% were concerned about the accuracy of information ChatGPT might generate on complex medical topics.

Conclusions: Medical students show strong interest and trust in using ChatGPT and similar chatbots for academic purposes but have concerns about the reliability of the information and potential misuse in medical education. The use of AI tools should follow ethical guidelines set by academic institutions, with regular updates to keep pace with technological progress. Future research should focus on the impact of AI on education and personal development, especially among young people.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11800517PMC
http://dx.doi.org/10.1186/s12909-025-06731-9DOI Listing

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