Objective: To conduct a systematic review and network meta-analysis on the effects of traditional Chinese fitness exercises on bone mineral density (BMD) among middle-aged and elderly individuals.
Methods: Randomized controlled trials were collected from seven electronic databases: PubMed, EMBASE, Web of Science, the Cochrane Library, CNKI, VIP, and Wan fang. Studies were selected according to the PICOS principles. Totally 27, 28, 12 and 16 studies pertaining to lumbar spine BMD, femoral neck BMD, greater trochanter BMD, and Ward's triangle BMD, respectively, were comprehensively collected. The effectiveness of various exercise interventions was compared via network meta-analysis using the surface under the cumulative ranking area (SUCRA) to rank effectiveness.
Results: Thirty one studies were included in the risk assessment and network meta-analysis. In the network diagrams formed by the four BMD outcome measures, closed loops were identified within sequences Ba DuanJin, Yi JinJing, and CON; sequences Ba DuanJin, Wu QinXi, and CON; sequences Yi JinJing, Wu QinXi, and CON, allowing for direct and indirect comparisons. Tai Chi, Ba DuanJin, Yi JinJing, and Wu QinXi affected BMD in varying ways. As for lumbar spine BMD, the effect of Yi JinJing was ranked first (SUCRA = 69.3 %), followed by Wu QinXi (SUCRA = 66.7 %). In femoral neck BMD, Ba DuanJin was most the effective (SUCRA = 64.9 %). Tai Chi was ranked the highest in both greater trochanter BMD (SUCRA = 66.7 %) and Ward's triangle BMD (SUCRA = 61.6 %). Inconsistency assessment showed high reliability.
Conclusion: Traditional Chinese exercises may provide safe and feasible interventions for improving BMD in middle-aged and elderly people. Although there are no significant differences among most interventions, the SUCRA rankings suggest each exercise has potential advantages in different areas, providing a reference for personalized bone health management.
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http://dx.doi.org/10.1016/j.ctcp.2025.101956 | DOI Listing |
Purpose: To compare anesthesia techniques (WALANT (wide-awake anesthesia no tourniquet), locoregional anesthesia, local anesthesia with tourniquet or sedation) for carpal tunnel release (CTR).
Methods: A comprehensive literature search was conducted on PubMed, MEDLINE, Embase and the Cochrane Library up to May 2023. Two independent reviewers selected the studies and extracted the data.
Purpose: A staged bilateral total knee arthroplasty (BTKA) procedure is considered when a patient is not deemed suitable for simultaneous BTKA due to concerns about the risk of mortality and complications. However, no network meta-analysis has been conducted to compare simultaneous vs staged BTKA procedures with different intervals in terms of postoperative mortality and overall complication rates.
Methods: Four databases - Medline, Embase, Cochrane Library and Web of Science - were searched from inception to December 19, 2023, for studies comparing patients who underwent staged BTKA with different intervals and simultaneous BTKA.
J Natl Cancer Inst
March 2025
School of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR.
Background: Cancer-related cognitive impairment is a common complication of cancer and its treatment. The effectiveness of Traditional Chinese Medicine (TCM)-based interventions in improving subjective and objective cognitive function has not yet been investigated in previous network meta-analyses. This study aimed to evaluate the comparative effectiveness of nonpharmacological interventions including TCM-based interventions, and to rank the best option for improving cognitive function among adults with non-central nervous system cancer.
View Article and Find Full Text PDFFront Immunol
March 2025
Second Department of Urology and Surgery, Affiliated Hospital of Hebei Engineering University, Handan, China.
Background: This study systematically reviews the efficacy and safety of the single or combined use of programmed factor 1 (PD-1)/programmed factor 1 ligand (PD-L1) inhibitors for treating metastatic or advanced renal cell carcinoma (RCC).
Methods: Relevant articles were collected for meta-analysis through searches on PubMed, Web of Science, Embase, Cochrane Library, and Clinical Trials, as well as for relevant randomized controlled experiments.
Results: Based on eleven studies, the effectiveness of the experimental group was found to be significantly better than the control in terms of overall survival (OS) [R=0.
Syst Rev
March 2025
Department of Cardiology, Guang'Anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Background: Chinese classical prescriptions (CCPs) are commonly utilized in China as an adjuvant treatment for dilated cardiomyopathy (DCM). Nevertheless, there was insufficient systematic evidence data to show the advantages of CCPs plus current conventional therapy (CT) against DCM. This network meta-analysis (NMA) sought to evaluate and prioritize the six different CCP types' respective efficacies for DCM.
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