Objective: To explore the clinical efficacy of small sub-eyebrow incision in severing the corrugator supercilii muscle combined with autologous block fat transplantation for treating severe frown lines.
Methodology: Sixteen patients with severe frown lines admitted to our hospital who refused to receive repeated injections of botulinum toxin were selected for treatment through corrugator dissection combined with fat transplantation.
Results: No patients had difficulty raising their eyebrows after surgery. They all had a smooth eyebrow shape, no abnormal movement of the eyebrows, and no tissue depression during relaxation or frowning. At 12 months after surgery, the overall patient satisfaction with the treatment was 100%, indicating satisfactory results.
Conclusion: Treating severe frown lines with a small incision of corrugator combined with autologous block fat transplantation is more effective than traditional treatment, maintains stable and long-term satisfaction, and is associated with less postoperative complications; therefore, this technique should be promoted for treating severe frown lines.
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http://dx.doi.org/10.2147/CCID.S492565 | DOI Listing |
Clin Cosmet Investig Dermatol
January 2025
Department Plastic Surgery, Affiliated Hospital of Shandong second Medical University, Weifang, People's Republic of China.
Objective: To explore the clinical efficacy of small sub-eyebrow incision in severing the corrugator supercilii muscle combined with autologous block fat transplantation for treating severe frown lines.
Methodology: Sixteen patients with severe frown lines admitted to our hospital who refused to receive repeated injections of botulinum toxin were selected for treatment through corrugator dissection combined with fat transplantation.
Results: No patients had difficulty raising their eyebrows after surgery.
Encephale
February 2025
Centre de bioéthique, université de Namur, Namur, Belgique. Electronic address:
In bioethics, patient autonomy is often considered a fundamental principle, even more important than beneficence, non-maleficence and justice. Inspired by liberal philosophies (such as J.S.
View Article and Find Full Text PDFAesthet Surg J
November 2024
Dermatologist in private practice, Hunt Valley, MD, USA.
Background: Botulinum neurotoxins used in aesthetic medicine require reconstitution before administration, which may be inconvenient and present errors among injectors.
Objectives: Evaluate the efficacy and safety of ready-to-use nivobotulinumtoxinA liquid formulation for the treatment of glabellar lines (GL) with/without treatment of lateral canthal lines (LCL).
Methods: Two multicenter, phase 3, double-blind, randomized trials enrolled participants with moderate-to-severe GL (Study 001) or moderate-to-severe GL+LCL (Study 005).
Dermatol Ther (Heidelb)
December 2024
Department of Surgery and Division of Plastic and Reconstructive Surgery, Tri-Service General Hospital, National Defense Medical Center, No.325, Sec. 2, Chenggong Rd., Neihu District, Taipei City, 114202, Taiwan, ROC.
Introduction: OBI-858 is a brand-new botulinum Type A complex toxin with a specific molecular weight of 760 kDa intended for development for both aesthetic and therapeutic applications. This is a phase I, dose-escalation study to evaluate the safety and preliminary efficacy of OBI-858 in subjects with moderate to severe glabellar lines.
Methods: Each subject received OBI-858 by intramuscular injections with an assigned dose (10 U, 20 U, and 30 U).
Background: Botulinum toxin (BT) has become one of the most frequently sought aesthetic procedures for wrinkle reduction.
Objective: This study investigated the effectiveness and safety of a novel device using radiofrequency (RF) and high-intensity facial muscle stimulation (HIFES) in patients injected with BT.
Methods: Twelve patients were divided into an Active (N=10) and a Control group (N=2), where the Active received four treatments and the Control none.
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