Objective: This study aims to establish normative data for the modified Location Learning Test (m-LLT), considering sociodemographic characteristics such as age, sex, and educational level.
Materials And Methods: One hundred eighty-nine middle-aged and elderly people aged 50 years and older were recruited from the French-speaking population in Quebec (Canada). The m-LLT procedure described by Kessels et al. (2006) was used. Percentiles were derived for performance scores (Trial 1, Total Displacement Score, Learning Index, Delayed Recall Displacements), stratified by sociodemographic characteristics where appropriate.
Results: Regarding the sex variable, the number of displacements in Trial 1 and for the Total Displacement Score were higher in men than in women. Age was positively associated with the Total Displacement Score and Delayed Recall Displacements and negatively associated with the Learning Index. Education was positively associated with the Learning Index and Delayed Recall Displacements. Two-thirds of the normative sample achieved a perfect score on the fifth and final learning trial.
Conclusions: Learning was better in women than in men, which may be explained by the use of verbal and nonverbal strategies and environmental awareness favoring women. The decline in learning and retrieval with age can be explained, among other reasons, by a less strategic approach during the encoding phase, a decline in other cognitive domains, or poorer imagery-based representations of the stimuli. The associations between education, strategic retrieval, and cognitive reserve are discussed. Overall, these normative data will enhance the detection of cognitive decline in geriatric clinical or research settings.
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http://dx.doi.org/10.1093/arclin/acaf009 | DOI Listing |
Soc Sci Med
February 2025
London School of Hygiene and Tropical Medicine, London, United Kingdom.
Cash or food transfers can reduce intimate partner violence (IPV), but knowledge gaps remain on how impacts evolve over time, and the role of complementary 'plus' activities and contextual factors. We conducted a mixed-method analysis of how the Transfer Modality Research Initiative in Bangladesh affected IPV over time. The programme was implemented from 2012 to 2014, following a randomised controlled trial (RCT) design, across Northern and Southern Bangladesh.
View Article and Find Full Text PDFElife
March 2025
Department of Complex Systems, Institute of Computer Science of the Czech Academy of Sciences, Prague, Czech Republic.
Longitudinal neuroimaging studies offer valuable insight into brain development, ageing, and disease progression over time. However, prevailing analytical approaches rooted in our understanding of population variation are primarily tailored for cross-sectional studies. To fully leverage the potential of longitudinal neuroimaging, we need methodologies that account for the complex interplay between population variation and individual dynamics.
View Article and Find Full Text PDFJMIR Form Res
March 2025
McLean Hospital, Harvard Medical School, 115 Mill Street, South Belknap, Belmont, US.
Background: Phenylketonuria (PKU) is a rare, hereditary disease that causes disruption in phenylalanine (Phe) metabolism. Despite early intervention, individuals with PKU may have difficulty in several different cognitive domains, including verbal fluency, processing speed, and executive functioning.
Objective: The overarching goal of the Evaluating Fluctuations in Cognitive and Speech Characteristics in Phenylketonuria study (CSP Study) is to characterize the relationships among cognition, speech, mood, and blood-based biomarkers (Phe, Tyr) in individuals with early treated PKU.
Eval Rev
March 2025
Graduate School of Education, Stanford University, Stanford, CA, USA.
The recognition that researcher discretion coupled with unconscious biases and motivated reasoning sometimes leads to false findings ("p-hacking") led to the broad embrace of study preregistration and other open-science practices in experimental research. Paradoxically, the preregistration of quasi-experimental studies remains uncommon although such studies involve far more discretionary decisions and are the most prevalent approach to making causal claims in the social sciences. I discuss several forms of recent empirical evidence indicating that questionable research practices contribute to the comparative unreliability of quasi-experimental research and advocate for adopting the preregistration of such studies.
View Article and Find Full Text PDFWomens Health (Lond)
March 2025
Center for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
Background: Retention of weight postpartum increases risk for long-term morbidity, including cardiometabolic disease. Although retained weight postpartum is a complex problem, interventions generally address individual diet and activity behaviors.
Objectives: We investigated the impact of social-network factors on postpartum health behaviors and weight.
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