Introduction And Importance: Hydatid disease, caused by Echinococcus larvae, leads to cystic echinococcosis, primarily affecting the liver and lungs. It is common in endemic regions like Argentina and East Africa, with incidences of over 50 cases per 100,000 people. A rare and life-threatening complication is the intraperitoneal rupture of a hydatid cyst.
Case Presentation: A 38-year-old female presented with epigastric pain followed by sudden-onset abdominal pain and hypotension. Lab results showed elevated white blood cell count with a high eosinophil. Ultrasonography (USG) and Computed Tomography (CT) scans showed a large, ruptured hydatid cyst of the liver. Emergency laparotomy revealed a ruptured hydatid cyst at the anterosuperior aspect of the liver. The intracystic collection was aspirated, and the cyst cavity and peritoneal cavity were washed with 20 % warm hypertonic saline. Postoperatively, albendazole treatment was started. Follow-up evaluations at 1, 3, and 6 months showed no evidence of recurrence on radiological scans.
Clinical Discussion: Intraperitoneal rupture of hydatid cysts is a rare yet life-threatening complication, accounting for 1-16 % of cases. USG and Contrast-Enhanced CT (CECT) of the abdomen are the mainstays for diagnosis, and magnetic resonance cholangiopancreatography (MRCP) helps detect cystobiliary communication. Treatment includes stabilization, surgical cyst evacuation, and scolicidal irrigation. Postoperative albendazole therapy, along with regular follow-up, is essential to prevent recurrence.
Conclusion: Spontaneous rupture of hepatic hydatid cyst with cystobiliary communication is a rare but critical condition, especially in endemic areas, presenting with acute abdomen and shock. Lifesaving emergency laparotomy followed by comprehensive postoperative care is vital for preventing complications and recurrence.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11840511 | PMC |
http://dx.doi.org/10.1016/j.ijscr.2025.111012 | DOI Listing |
J Genet Eng Biotechnol
March 2025
State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, China; Department of Hepatobiliary and Echinococcosis Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China. Electronic address:
Background: Few studies revealed that stromal genes regulate the tumor microenvironment (TME). However, identification of key-risk genes in the invasive ductal breast carcinoma-associated stroma (IDBCS) and their associations with the prediction of risk group remains lacking.
Methods: This study used the GSE9014, GSE10797, GSE8977, GSE33692, and TGGA BRCA datasets.
Objective: This study aimed to investigate the role of Raf kinase inhibitor protein (RKIP) in degranulation induced by echinococcal cyst fluid (EgCF) in bone marrow-derived mast cells (BMMCs).
Methods: Primary BMMCs were isolated and cultured from the femurs and tibias of RKIP gene knockout (KO) and wild-type (WT) C57BL/6 mice. EgCF-induced degranulation models were established for both groups.
Cells
February 2025
College of Veterinary Medicine, Jilin University, Changchun 130062, China.
(1) Background: (CE) is an -induced worldwide parasitic zoonosis and is a recognized public health and socio-economic concern. The liver is the major target organ for CE's infective form protoscolex (PSCs), which causes serious liver damage and endangers the host's life. Reports show that PSC infection causes liver cell Fe metabolism disorder and abnormal deposition of Fe in liver cells and results in liver cell death.
View Article and Find Full Text PDFPediatr Pulmonol
March 2025
Department of Pediatrics, Ankura Hospital for Women and Children, Vijayawada, Andhra Pradesh, India.
Eur J Breast Health
March 2025
University of Sousse, Faculty of Medicine of Sousse, Department of Obstetrics and Gynecology, Farhat Hached University Hospital, Sousse, Tunisia.
Although rare, a hydatid cyst of the breast represents a mammary pseudotumor. We present the case of a 49-year-old woman with no significant medical history, who was diagnosed with an isolated hydatid cyst of the breast confirmed by histopathological examination. This patient consulted for breast asymmetry and a feeling of heaviness in the left breast, with no clinical signs of systemic hydatidosis.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!